Nickel in PDB 1fcp: Ferric Hydroxamate Uptake Receptor (Fhua) From E.Coli in Complex with Bound Ferrichrome-Iron

The structure of Ferric Hydroxamate Uptake Receptor (Fhua) From E.Coli in Complex with Bound Ferrichrome-Iron, PDB code: 1fcp was solved by E.Hofmann, A.D.Ferguson, K.Diederichs, W.Welte, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	40.00 / 2.70
Space group	P 61
Cell size a, b, c (Å), α, β, γ (°)	171.400, 171.400, 85.700, 90.00, 90.00, 120.00
R / Rfree (%)	23.2 / 28.1

The structure of Ferric Hydroxamate Uptake Receptor (Fhua) From E.Coli in Complex with Bound Ferrichrome-Iron also contains other interesting chemical elements:

Iron

(Fe)

1 atom

The binding sites of Nickel atom in the Ferric Hydroxamate Uptake Receptor (Fhua) From E.Coli in Complex with Bound Ferrichrome-Iron (pdb code 1fcp). This binding sites where shown within 5.0 Angstroms radius around Nickel atom.
In total 2 binding sites of Nickel where determined in the Ferric Hydroxamate Uptake Receptor (Fhua) From E.Coli in Complex with Bound Ferrichrome-Iron, PDB code: 1fcp:
Jump to Nickel binding site number: 1; 2;

Nickel binding site 1 out of 2 in the Ferric Hydroxamate Uptake Receptor (Fhua) From E.Coli in Complex with Bound Ferrichrome-Iron


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 1 of Ferric Hydroxamate Uptake Receptor (Fhua) From E.Coli in Complex with Bound Ferrichrome-Iron within 5.0Å range: probe atom residue distance (Å) B Occ A:Ni1011 b:98.8 occ:1.00 O10 A:GPH1005 1.9 0.2 1.0 O A:HOH1027 2.4 42.3 1.0 O A:HOH1014 2.9 36.2 1.0 P1 A:GPH1005 2.9 0.2 1.0 O9 A:GPH1005 3.2 69.3 1.0 O8 A:GPH1005 3.8 0.2 1.0 O4 A:GPH1005 4.1 0.5 1.0 C4 A:GPH1005 4.6 96.4 1.0 C3 A:GPH1005 4.7 82.3 1.0 O5 A:GLC1006 5.0 77.6 1.0

Nickel binding site 2 out of 2 in the Ferric Hydroxamate Uptake Receptor (Fhua) From E.Coli in Complex with Bound Ferrichrome-Iron


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 2 of Ferric Hydroxamate Uptake Receptor (Fhua) From E.Coli in Complex with Bound Ferrichrome-Iron within 5.0Å range: probe atom residue distance (Å) B Occ A:Ni1012 b:0.3 occ:1.00 O7B A:GP1902 2.1 79.4 1.0 P4B A:GP1902 3.1 90.7 1.0 O1B A:GP1902 3.2 73.5 1.0 N2B A:GP1902 3.2 79.4 1.0 NZ A:LYS439 3.3 93.4 1.0 O9B A:GP1902 3.8 0.4 1.0 C1B A:GP1902 3.8 66.4 1.0 CE A:LYS439 3.9 90.0 1.0 C2B A:GP1902 4.0 60.7 1.0 C1J A:LIM906 4.1 82.5 1.0 C2J A:LIM906 4.1 65.0 1.0 O8B A:GP1902 4.4 65.0 1.0 O2J A:LIM906 4.7 76.1 1.0

A.D.Ferguson, E.Hofmann, J.W.Coulton, K.Diederichs, W.Welte. Siderophore-Mediated Iron Transport: Crystal Structure of Fhua with Bound Lipopolysaccharide. Science V. 282 2215 1998.
ISSN: ISSN 0036-8075
PubMed: 9856937
DOI: 10.1126/SCIENCE.282.5397.2215