Nickel in PDB 2aie: S.Pneumoniae Polypeptide Deformylase Complexed with Sb- 505684

All present enzymatic activity of S.Pneumoniae Polypeptide Deformylase Complexed with Sb- 505684:
3.5.1.88;

The structure of S.Pneumoniae Polypeptide Deformylase Complexed with Sb- 505684, PDB code: 2aie was solved by K.J.Smith, C.M.Petit, K.Aubart, M.Smyth, E.Mcmanus, J.Jones, A.Fosberry, C.Lewis, M.Lonetto, S.B.Christensen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 1.70
Space group	P 43
Cell size a, b, c (Å), α, β, γ (°)	49.672, 49.672, 92.161, 90.00, 90.00, 90.00
R / Rfree (%)	22.7 / 25.8

The binding sites of Nickel atom in the S.Pneumoniae Polypeptide Deformylase Complexed with Sb- 505684 (pdb code 2aie). This binding sites where shown within 5.0 Angstroms radius around Nickel atom.
In total only one binding site of Nickel was determined in the S.Pneumoniae Polypeptide Deformylase Complexed with Sb- 505684, PDB code: 2aie:

Nickel binding site 1 out of 1 in the S.Pneumoniae Polypeptide Deformylase Complexed with Sb- 505684


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 1 of S.Pneumoniae Polypeptide Deformylase Complexed with Sb- 505684 within 5.0Å range: probe atom residue distance (Å) B Occ P:Ni502 b:31.1 occ:1.00 NE2 P:HIS177 2.1 19.8 1.0 NE2 P:HIS173 2.2 24.3 1.0 O21 P:SB9501 2.2 32.2 1.0 O24 P:SB9501 2.3 21.8 1.0 SG P:CYS130 2.4 23.8 1.0 C23 P:SB9501 2.8 28.1 1.0 N18 P:SB9501 2.8 31.0 1.0 CE1 P:HIS177 3.1 18.9 1.0 CD2 P:HIS173 3.1 22.2 1.0 CD2 P:HIS177 3.1 18.8 1.0 CE1 P:HIS173 3.2 24.6 1.0 NE2 P:GLN76 3.4 22.4 1.0 CB P:CYS130 3.5 23.3 1.0 O P:HOH3037 3.6 25.0 1.0 CA P:CYS130 3.9 24.6 1.0 CD P:GLN76 4.0 22.6 1.0 OE1 P:GLN76 4.2 21.1 1.0 C15 P:SB9501 4.2 32.0 1.0 ND1 P:HIS177 4.2 18.6 1.0 CG P:HIS173 4.3 20.7 1.0 CG P:HIS177 4.3 18.0 1.0 ND1 P:HIS173 4.3 24.6 1.0 N P:LEU131 4.3 26.4 1.0 C12 P:SB9501 4.6 32.8 1.0 OE2 P:GLU174 4.6 22.6 1.0 C P:CYS130 4.6 26.0 1.0 O P:HOH3009 4.6 18.9 1.0 O P:GLY129 4.7 24.7 1.0 OE1 P:GLU174 4.8 21.1 1.0

K.J.Smith, C.M.Petit, K.Aubart, M.Smyth, E.Mcmanus, J.Jones, A.Fosberry, C.Lewis, M.Lonetto, S.B.Christensen. Structural Variation and Inhibitor Binding in Polypeptide Deformylase From Four Different Bacterial Species Protein Sci. V. 12 349 2003.
ISSN: ISSN 0961-8368
PubMed: 12538898
DOI: 10.1110/PS.0229303