Atomistry » Nickel » PDB 2c21-2gw3 » 2cg5
Atomistry »
  Nickel »
    PDB 2c21-2gw3 »
      2cg5 »

Nickel in PDB 2cg5: Structure of Aminoadipate-Semialdehyde Dehydrogenase- Phosphopantetheinyl Transferase in Complex with Cytosolic Acyl Carrier Protein and Coenzyme A

Enzymatic activity of Structure of Aminoadipate-Semialdehyde Dehydrogenase- Phosphopantetheinyl Transferase in Complex with Cytosolic Acyl Carrier Protein and Coenzyme A

All present enzymatic activity of Structure of Aminoadipate-Semialdehyde Dehydrogenase- Phosphopantetheinyl Transferase in Complex with Cytosolic Acyl Carrier Protein and Coenzyme A:
1.2.1.31; 2.3.1.85;

Protein crystallography data

The structure of Structure of Aminoadipate-Semialdehyde Dehydrogenase- Phosphopantetheinyl Transferase in Complex with Cytosolic Acyl Carrier Protein and Coenzyme A, PDB code: 2cg5 was solved by G.Bunkoczi, A.Joshi, E.Papagrigoriu, C.Arrowsmith, A.Edwards, M.Sundstrom, J.Weigelt, F.Von Delft, S.Smith, U.Oppermann, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 50.00 / 2.70
Space group P 32 2 1
Cell size a, b, c (Å), α, β, γ (°) 69.361, 69.361, 184.715, 90.00, 90.00, 120.00
R / Rfree (%) 19.2 / 24.7

Other elements in 2cg5:

The structure of Structure of Aminoadipate-Semialdehyde Dehydrogenase- Phosphopantetheinyl Transferase in Complex with Cytosolic Acyl Carrier Protein and Coenzyme A also contains other interesting chemical elements:

Magnesium (Mg) 2 atoms

Nickel Binding Sites:

The binding sites of Nickel atom in the Structure of Aminoadipate-Semialdehyde Dehydrogenase- Phosphopantetheinyl Transferase in Complex with Cytosolic Acyl Carrier Protein and Coenzyme A (pdb code 2cg5). This binding sites where shown within 5.0 Angstroms radius around Nickel atom.
In total only one binding site of Nickel was determined in the Structure of Aminoadipate-Semialdehyde Dehydrogenase- Phosphopantetheinyl Transferase in Complex with Cytosolic Acyl Carrier Protein and Coenzyme A, PDB code: 2cg5:

Nickel binding site 1 out of 1 in 2cg5

Go back to Nickel Binding Sites List in 2cg5
Nickel binding site 1 out of 1 in the Structure of Aminoadipate-Semialdehyde Dehydrogenase- Phosphopantetheinyl Transferase in Complex with Cytosolic Acyl Carrier Protein and Coenzyme A


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 1 of Structure of Aminoadipate-Semialdehyde Dehydrogenase- Phosphopantetheinyl Transferase in Complex with Cytosolic Acyl Carrier Protein and Coenzyme A within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ni1302

b:63.9
occ:0.50
 N A:GLY149 3.3 58.2 1.0
NH1 B:ARG2138 3.5 56.5 1.0
ND1 B:HIS2133 3.5 53.3 1.0
O A:HOH2011 3.5 47.8 1.0
CA A:ARG148 3.9 58.7 1.0
C A:ARG148 4.1 58.2 1.0
O A:GLY147 4.1 59.1 1.0
CA A:GLY149 4.2 57.7 1.0
CE1 B:HIS2133 4.2 54.2 1.0
O A:HOH2010 4.3 44.8 1.0
CG B:HIS2133 4.5 54.0 1.0
CZ B:ARG2138 4.6 55.7 1.0
CB A:ARG148 4.6 59.1 1.0
O A:HOH2013 4.7 54.3 1.0
CB B:HIS2133 4.7 54.3 1.0
N A:ARG148 4.8 58.7 1.0
C A:GLY147 4.8 58.8 1.0
NH2 B:ARG2138 4.9 56.1 1.0
CG A:ARG148 4.9 60.8 1.0
O A:GLY149 4.9 58.1 1.0
C A:GLY149 5.0 57.7 1.0

Reference:

G.Bunkoczi, S.Pasta, A.Joshi, X.Wu, K.L.Kavanagh, S.Smith, U.Oppermann. Mechanism and Substrate Recognition of Human Holo Acp Synthase. Chem.Biol. V. 14 1243 2007.
ISSN: ISSN 1074-5521
PubMed: 18022563
DOI: 10.1016/J.CHEMBIOL.2007.10.013
Page generated: Wed Oct 9 16:41:28 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy