Nickel in PDB 2wqn: Structure of Adp-Bound Human NEK7

All present enzymatic activity of Structure of Adp-Bound Human NEK7:
2.7.11.1;

The structure of Structure of Adp-Bound Human NEK7, PDB code: 2wqn was solved by M.W.Richards, R.Bayliss, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.180 / 2.30
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	46.835, 133.108, 131.851, 90.00, 90.00, 90.00
R / Rfree (%)	19.06 / 22.05

The structure of Structure of Adp-Bound Human NEK7 also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Nickel atom in the Structure of Adp-Bound Human NEK7 (pdb code 2wqn). This binding sites where shown within 5.0 Angstroms radius around Nickel atom.
In total only one binding site of Nickel was determined in the Structure of Adp-Bound Human NEK7, PDB code: 2wqn:

Nickel binding site 1 out of 1 in the Structure of Adp-Bound Human NEK7


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 1 of Structure of Adp-Bound Human NEK7 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ni1302 b:44.7 occ:0.50 NE2 A:HIS209 2.1 46.2 1.0 SG A:CYS247 2.4 46.0 1.0 CE1 A:HIS209 3.0 44.2 1.0 CD2 A:HIS209 3.2 47.0 1.0 CB A:CYS247 3.4 50.7 1.0 ND1 A:HIS209 4.2 43.6 1.0 CG A:HIS209 4.3 45.4 1.0 O A:HOH2093 4.4 79.1 1.0 CA A:CYS247 4.8 49.3 1.0

M.W.Richards, L.O'regan, C.Mas-Droux, J.M.Blot, J.Cheung, S.Hoelder, A.M.Fry, R.Bayliss. An Autoinhibitory Tyrosine Motif in the Cell-Cycle- Regulated NEK7 Kinase Is Released Through Binding of NEK9. Mol.Cell V. 36 560 2009.
ISSN: ISSN 1097-2765
PubMed: 19941817
DOI: 10.1016/J.MOLCEL.2009.09.038