Atomistry » Nickel » PDB 3dse-3hy3 » 3dse
Atomistry »
  Nickel »
    PDB 3dse-3hy3 »
      3dse »

Nickel in PDB 3dse: A Potent Peptidomimetic Inhibitor of Botulinum Neurotoxin Serotype A Has A Very Different Conformation Than Snap-25 Substrate

Enzymatic activity of A Potent Peptidomimetic Inhibitor of Botulinum Neurotoxin Serotype A Has A Very Different Conformation Than Snap-25 Substrate

All present enzymatic activity of A Potent Peptidomimetic Inhibitor of Botulinum Neurotoxin Serotype A Has A Very Different Conformation Than Snap-25 Substrate:
3.4.24.69;

Protein crystallography data

The structure of A Potent Peptidomimetic Inhibitor of Botulinum Neurotoxin Serotype A Has A Very Different Conformation Than Snap-25 Substrate, PDB code: 3dse was solved by J.E.Zuniga, T.Fenn, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 45.00 / 1.90
Space group P 21 21 2
Cell size a, b, c (Å), α, β, γ (°) 56.798, 191.054, 42.149, 90.00, 90.00, 90.00
R / Rfree (%) 17.9 / 24.3

Other elements in 3dse:

The structure of A Potent Peptidomimetic Inhibitor of Botulinum Neurotoxin Serotype A Has A Very Different Conformation Than Snap-25 Substrate also contains other interesting chemical elements:

Zinc (Zn) 1 atom

Nickel Binding Sites:

The binding sites of Nickel atom in the A Potent Peptidomimetic Inhibitor of Botulinum Neurotoxin Serotype A Has A Very Different Conformation Than Snap-25 Substrate (pdb code 3dse). This binding sites where shown within 5.0 Angstroms radius around Nickel atom.
In total only one binding site of Nickel was determined in the A Potent Peptidomimetic Inhibitor of Botulinum Neurotoxin Serotype A Has A Very Different Conformation Than Snap-25 Substrate, PDB code: 3dse:

Nickel binding site 1 out of 1 in 3dse

Go back to Nickel Binding Sites List in 3dse
Nickel binding site 1 out of 1 in the A Potent Peptidomimetic Inhibitor of Botulinum Neurotoxin Serotype A Has A Very Different Conformation Than Snap-25 Substrate


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 1 of A Potent Peptidomimetic Inhibitor of Botulinum Neurotoxin Serotype A Has A Very Different Conformation Than Snap-25 Substrate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ni502

b:20.2
occ:1.00
NZ A:LYS272 2.2 18.7 1.0
O A:HOH600 2.2 18.3 1.0
CE1 A:HIS269 2.2 16.7 1.0
O A:HOH601 2.2 21.9 1.0
O A:HOH1105 2.3 15.3 1.0
NE2 A:HIS269 2.9 17.1 1.0
CE A:LYS272 3.1 19.6 1.0
ND1 A:HIS269 3.3 20.9 1.0
CD2 A:HIS269 4.1 11.5 1.0
CG A:HIS269 4.4 14.8 1.0
CD A:LYS272 4.4 21.6 1.0

Reference:

J.E.Zuniga, J.J.Schmidt, T.Fenn, J.C.Burnett, D.Arac, R.Gussio, R.G.Stafford, S.S.Badie, S.Bavari, A.T.Brunger. A Potent Peptidomimetic Inhibitor of Botulinum Neurotoxin Serotype A Has A Very Different Conformation Than Snap-25 Substrate Structure V. 16 1588 2008.
ISSN: ISSN 0969-2126
PubMed: 18940613
DOI: 10.1016/J.STR.2008.07.011
Page generated: Wed Dec 16 01:23:33 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy