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Nickel in PDB 4bo3: Crystal Structure of 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase (Fabg) From Pseudomonas Aeruginosa in Complex with 2-(3-(Trifluoromethyl)Anilino)Pyridine-3-Sulfonamide at 2.5A Resolution
Enzymatic activity of Crystal Structure of 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase (Fabg) From Pseudomonas Aeruginosa in Complex with 2-(3-(Trifluoromethyl)Anilino)Pyridine-3-Sulfonamide at 2.5A Resolution
All present enzymatic activity of Crystal Structure of 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase (Fabg) From Pseudomonas Aeruginosa in Complex with 2-(3-(Trifluoromethyl)Anilino)Pyridine-3-Sulfonamide at 2.5A Resolution:
1.1.1.100;
1.1.1.100;
Protein crystallography data
The structure of Crystal Structure of 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase (Fabg) From Pseudomonas Aeruginosa in Complex with 2-(3-(Trifluoromethyl)Anilino)Pyridine-3-Sulfonamide at 2.5A Resolution, PDB code: 4bo3
was solved by
C.D.Cukier,
R.Schnell,
Y.Lindqvist,
G.Schneider,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 38.89 / 2.50 |
| Space group | P 21 21 21 |
| Cell size a, b, c (Å), α, β, γ (°) | 55.210, 109.402, 148.615, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 23.183 / 28.103 |
Other elements in 4bo3:
The structure of Crystal Structure of 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase (Fabg) From Pseudomonas Aeruginosa in Complex with 2-(3-(Trifluoromethyl)Anilino)Pyridine-3-Sulfonamide at 2.5A Resolution also contains other interesting chemical elements:
| Fluorine | (F) | 6 atoms |
Nickel Binding Sites:
The binding sites of Nickel atom in the Crystal Structure of 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase (Fabg) From Pseudomonas Aeruginosa in Complex with 2-(3-(Trifluoromethyl)Anilino)Pyridine-3-Sulfonamide at 2.5A Resolution
(pdb code 4bo3). This binding sites where shown within
5.0 Angstroms radius around Nickel atom.
In total only one binding site of Nickel was determined in the Crystal Structure of 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase (Fabg) From Pseudomonas Aeruginosa in Complex with 2-(3-(Trifluoromethyl)Anilino)Pyridine-3-Sulfonamide at 2.5A Resolution, PDB code: 4bo3:
In total only one binding site of Nickel was determined in the Crystal Structure of 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase (Fabg) From Pseudomonas Aeruginosa in Complex with 2-(3-(Trifluoromethyl)Anilino)Pyridine-3-Sulfonamide at 2.5A Resolution, PDB code: 4bo3:
Nickel binding site 1 out of 1 in 4bo3
Go back to
Nickel Binding Sites List in 4bo3
Nickel binding site 1 out
of 1 in the Crystal Structure of 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase (Fabg) From Pseudomonas Aeruginosa in Complex with 2-(3-(Trifluoromethyl)Anilino)Pyridine-3-Sulfonamide at 2.5A Resolution
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Nickel with other atoms in the Ni binding
site number 1 of Crystal Structure of 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase (Fabg) From Pseudomonas Aeruginosa in Complex with 2-(3-(Trifluoromethyl)Anilino)Pyridine-3-Sulfonamide at 2.5A Resolution within 5.0Å range:
|
Reference:
C.D.Cukier,
A.Hope,
A.Elamin,
L.Moynie,
R.Schnell,
S.Schach,
H.Kneuper,
M.Singh,
J.Naismith,
Y.Lindqvist,
D.Gray,
G.Schneider.
Discovery of An Allosteric Inhibitor Binding Site in 3-Oxo-Acyl-Acp Reductase From Pseudomonas Aeruginosa Acs Chem.Biol. V. 8 2518 2013.
ISSN: ISSN 1554-8929
PubMed: 24015914
DOI: 10.1021/CB4005063
Page generated: Wed Dec 16 01:29:13 2020
ISSN: ISSN 1554-8929
PubMed: 24015914
DOI: 10.1021/CB4005063
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