Nickel in PDB 4c25: L-Fuculose 1-Phosphate Aldolase

All present enzymatic activity of L-Fuculose 1-Phosphate Aldolase:
4.1.2.17;

The structure of L-Fuculose 1-Phosphate Aldolase, PDB code: 4c25 was solved by M.A.Higgins, M.D.L.Suits, C.Marsters, A.B.Boraston, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	80.25 / 2.03
Space group	I 4
Cell size a, b, c (Å), α, β, γ (°)	113.490, 113.490, 41.300, 90.00, 90.00, 90.00
R / Rfree (%)	22.312 / 27.799

The structure of L-Fuculose 1-Phosphate Aldolase also contains other interesting chemical elements:

Zinc

(Zn)

1 atom

The binding sites of Nickel atom in the L-Fuculose 1-Phosphate Aldolase (pdb code 4c25). This binding sites where shown within 5.0 Angstroms radius around Nickel atom.
In total only one binding site of Nickel was determined in the L-Fuculose 1-Phosphate Aldolase, PDB code: 4c25:

Nickel binding site 1 out of 1 in the L-Fuculose 1-Phosphate Aldolase


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 1 of L-Fuculose 1-Phosphate Aldolase within 5.0Å range: probe atom residue distance (Å) B Occ A:Ni302 b:49.1 occ:1.00 N A:SER-3 1.9 54.0 1.0 N A:HIS-2 1.9 48.5 1.0 ND1 A:HIS-2 2.0 42.4 1.0 N A:GLY-4 2.6 50.2 1.0 C A:SER-3 2.7 52.3 1.0 CA A:SER-3 2.8 54.2 1.0 C A:GLY-4 2.8 48.2 1.0 CG A:HIS-2 2.9 44.5 1.0 CA A:GLY-4 2.9 45.2 1.0 CA A:HIS-2 3.0 47.1 1.0 CE1 A:HIS-2 3.0 41.0 1.0 CB A:HIS-2 3.1 42.8 1.0 O A:HOH2002 3.3 47.2 1.0 N A:MET-1 3.7 44.1 1.0 C A:HIS-2 3.9 43.8 1.0 O A:SER-3 3.9 57.1 1.0 O A:GLY-4 3.9 52.9 1.0 CD2 A:HIS-2 4.0 46.0 1.0 CB A:SER-3 4.1 57.5 1.0 NE2 A:HIS-2 4.1 46.5 1.0 OG A:SER-3 4.2 65.3 1.0 CA A:MET-1 5.0 52.1 1.0

M.A.Higgins, M.D.Suits, C.Marsters, A.B.Boraston. Structural and Functional Analysis of Fucose-Processing Enzymes From Streptococcus Pneumoniae. J.Mol.Biol. V. 426 1469 2014.
ISSN: ISSN 0022-2836
PubMed: 24333485
DOI: 10.1016/J.JMB.2013.12.006