Atomistry » Nickel » PDB 4w6f-4z42 » 4x68
Atomistry »
  Nickel »
    PDB 4w6f-4z42 »
      4x68 »

Nickel in PDB 4x68: Crystal Structure of OP0595 Complexed with Ampc

Enzymatic activity of Crystal Structure of OP0595 Complexed with Ampc

All present enzymatic activity of Crystal Structure of OP0595 Complexed with Ampc:
3.5.2.6;

Protein crystallography data

The structure of Crystal Structure of OP0595 Complexed with Ampc, PDB code: 4x68 was solved by M.Yamada, T.Watanabe, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 50.00 / 1.68
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 74.027, 54.781, 75.667, 90.00, 90.80, 90.00
R / Rfree (%) 21.2 / 24.8

Nickel Binding Sites:

The binding sites of Nickel atom in the Crystal Structure of OP0595 Complexed with Ampc (pdb code 4x68). This binding sites where shown within 5.0 Angstroms radius around Nickel atom.
In total 2 binding sites of Nickel where determined in the Crystal Structure of OP0595 Complexed with Ampc, PDB code: 4x68:
Jump to Nickel binding site number: 1; 2;

Nickel binding site 1 out of 2 in 4x68

Go back to Nickel Binding Sites List in 4x68
Nickel binding site 1 out of 2 in the Crystal Structure of OP0595 Complexed with Ampc


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 1 of Crystal Structure of OP0595 Complexed with Ampc within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ni402

b:75.0
occ:1.00
OD2 A:ASP360 2.3 31.1 1.0
NE2 A:HIS267 3.1 27.3 1.0
CD2 A:HIS267 3.4 26.3 1.0
CG A:ASP360 3.6 24.9 1.0
CB A:ASP360 4.3 22.3 1.0
CE1 A:HIS267 4.3 26.7 1.0
OD1 A:ASP360 4.5 29.4 1.0
CG A:HIS267 4.7 25.2 1.0
O A:PRO357 4.7 19.2 1.0
O A:LEU266 4.7 19.9 1.0
O A:HOH527 5.0 33.1 1.0

Nickel binding site 2 out of 2 in 4x68

Go back to Nickel Binding Sites List in 4x68
Nickel binding site 2 out of 2 in the Crystal Structure of OP0595 Complexed with Ampc


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 2 of Crystal Structure of OP0595 Complexed with Ampc within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ni403

b:77.3
occ:1.00
NE2 B:HIS267 2.6 24.7 1.0
OD1 B:ASP360 2.7 31.0 1.0
OD2 A:ASP149 2.8 35.2 1.0
OD2 B:ASP360 3.0 30.6 1.0
CD2 B:HIS267 3.1 23.6 1.0
CG B:ASP360 3.2 26.6 1.0
CE1 B:HIS267 3.8 24.0 1.0
CG A:ASP149 3.9 32.1 1.0
CG B:HIS267 4.4 21.9 1.0
ND1 B:HIS267 4.7 23.2 1.0
CB B:ASP360 4.7 23.5 1.0
O B:LEU266 4.7 18.8 1.0
OD1 A:ASP149 4.7 34.7 1.0
CB A:ASP149 4.7 30.1 1.0
O A:HOH615 4.9 28.6 1.0

Reference:

A.Morinaka, Y.Tsutsumi, M.Yamada, K.Suzuki, T.Watanabe, T.Abe, T.Furuuchi, S.Inamura, Y.Sakamaki, N.Mitsuhashi, T.Ida, D.M.Livermore. OP0595, A New Diazabicyclooctane: Mode of Action As A Serine Beta-Lactamase Inhibitor, Antibiotic and Beta-Lactam 'Enhancer' J.Antimicrob.Chemother. V. 70 2779 2015.
ISSN: ESSN 1460-2091
PubMed: 26089439
DOI: 10.1093/JAC/DKV166
Page generated: Wed Dec 16 01:37:41 2020

Last articles

Zn in 7L0B
Zn in 7KZZ
Zn in 7KZL
Zn in 7L3O
Zn in 7L52
Zn in 7L6T
Zn in 7KZ7
Zn in 7L6R
Zn in 7KKM
Zn in 7KKQ
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy