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Atomistry » Nickel » PDB 4z8g-5bnc » 5a3t | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Nickel » PDB 4z8g-5bnc » 5a3t » |
Nickel in PDB 5a3t: Crystal Structure of Human Plu-1 (JARID1B) in Complex with KDM5-C49 (2-(((2-((2-(Dimethylamino)Ethyl)(Ethyl)Amino)-2- Oxoethyl)Amino)Methyl) Isonicotinic Acid).Protein crystallography data
The structure of Crystal Structure of Human Plu-1 (JARID1B) in Complex with KDM5-C49 (2-(((2-((2-(Dimethylamino)Ethyl)(Ethyl)Amino)-2- Oxoethyl)Amino)Methyl) Isonicotinic Acid)., PDB code: 5a3t
was solved by
V.Srikannathasan,
C.Johansson,
C.Gileadi,
J.Kopec,
C.Strain-Damerell,
K.Kupinska,
N.A.Burgessbrown,
F.Von Delft,
C.H.Arrowsmith,
C.Bountra,
A.M.Edwards,
U.Oppermann,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5a3t:
The structure of Crystal Structure of Human Plu-1 (JARID1B) in Complex with KDM5-C49 (2-(((2-((2-(Dimethylamino)Ethyl)(Ethyl)Amino)-2- Oxoethyl)Amino)Methyl) Isonicotinic Acid). also contains other interesting chemical elements:
Nickel Binding Sites:
The binding sites of Nickel atom in the Crystal Structure of Human Plu-1 (JARID1B) in Complex with KDM5-C49 (2-(((2-((2-(Dimethylamino)Ethyl)(Ethyl)Amino)-2- Oxoethyl)Amino)Methyl) Isonicotinic Acid).
(pdb code 5a3t). This binding sites where shown within
5.0 Angstroms radius around Nickel atom.
In total only one binding site of Nickel was determined in the Crystal Structure of Human Plu-1 (JARID1B) in Complex with KDM5-C49 (2-(((2-((2-(Dimethylamino)Ethyl)(Ethyl)Amino)-2- Oxoethyl)Amino)Methyl) Isonicotinic Acid)., PDB code: 5a3t: Nickel binding site 1 out of 1 in 5a3tGo back to Nickel Binding Sites List in 5a3t
Nickel binding site 1 out
of 1 in the Crystal Structure of Human Plu-1 (JARID1B) in Complex with KDM5-C49 (2-(((2-((2-(Dimethylamino)Ethyl)(Ethyl)Amino)-2- Oxoethyl)Amino)Methyl) Isonicotinic Acid).
Mono view Stereo pair view
Reference:
C.Johansson,
S.Velupillai,
A.Tumber,
A.Szykowska,
E.S.Hookway,
R.P.Nowak,
C.Strain-Damerell,
C.Gileadi,
M.Philpott,
N.Burgess-Brown,
N.Wu,
J.Kopec,
A.Nuzzi,
H.Steuber,
U.Egner,
V.Badock,
S.Munro,
N.B.Lathangue,
S.Westaway,
J.Brown,
N.Athanasou,
R.Prinjha,
P.E.Brennan,
U.Oppermann.
Structural Analysis of Human KDM5B Guides Histone Demethylase Inhibitor Development. Nat.Chem.Biol. V. 12 539 2016.
Page generated: Wed Dec 16 01:38:48 2020
ISSN: ISSN 1552-4450 PubMed: 27214403 DOI: 10.1038/NCHEMBIO.2087 |
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