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Atomistry » Nickel » PDB 5bu6-5e6j » 5bui » |
Nickel in PDB 5bui: ERK2 Complexed with 2-Pyridiyl TetrahydroazaindazoleEnzymatic activity of ERK2 Complexed with 2-Pyridiyl Tetrahydroazaindazole
All present enzymatic activity of ERK2 Complexed with 2-Pyridiyl Tetrahydroazaindazole:
2.7.11.24; Protein crystallography data
The structure of ERK2 Complexed with 2-Pyridiyl Tetrahydroazaindazole, PDB code: 5bui
was solved by
C.R.Bellamacina,
W.Shu,
D.E.Bussiere,
J.T.Bagdanoff,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5bui:
The structure of ERK2 Complexed with 2-Pyridiyl Tetrahydroazaindazole also contains other interesting chemical elements:
Nickel Binding Sites:
The binding sites of Nickel atom in the ERK2 Complexed with 2-Pyridiyl Tetrahydroazaindazole
(pdb code 5bui). This binding sites where shown within
5.0 Angstroms radius around Nickel atom.
In total only one binding site of Nickel was determined in the ERK2 Complexed with 2-Pyridiyl Tetrahydroazaindazole, PDB code: 5bui: Nickel binding site 1 out of 1 in 5buiGo back to Nickel Binding Sites List in 5bui
Nickel binding site 1 out
of 1 in the ERK2 Complexed with 2-Pyridiyl Tetrahydroazaindazole
Mono view Stereo pair view
Reference:
J.T.Bagdanoff,
R.Jain,
W.Han,
D.Poon,
P.S.Lee,
C.Bellamacina,
M.Lindvall.
Ligand Efficient Tetrahydro-Pyrazolopyridines As Inhibitors of ERK2 Kinase. Bioorg.Med.Chem.Lett. V. 25 3626 2015.
Page generated: Wed Dec 16 01:40:18 2020
ISSN: ESSN 1464-3405 PubMed: 26144345 DOI: 10.1016/J.BMCL.2015.06.063 |
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