Nickel in PDB 5e6j: Structure of Sars Plpro Bound to A LYS48-Linked Di-Ubiquitin Activity Based Probe

All present enzymatic activity of Structure of Sars Plpro Bound to A LYS48-Linked Di-Ubiquitin Activity Based Probe:
2.7.7.48; 3.4.19.12; 3.4.22.69; 3.6.4.12; 3.6.4.13;

The structure of Structure of Sars Plpro Bound to A LYS48-Linked Di-Ubiquitin Activity Based Probe, PDB code: 5e6j was solved by C.D.Lima, M.Bekes, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.22 / 2.85
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	72.981, 68.239, 119.021, 90.00, 103.21, 90.00
R / Rfree (%)	23.2 / 26.4

The binding sites of Nickel atom in the Structure of Sars Plpro Bound to A LYS48-Linked Di-Ubiquitin Activity Based Probe (pdb code 5e6j). This binding sites where shown within 5.0 Angstroms radius around Nickel atom.
In total only one binding site of Nickel was determined in the Structure of Sars Plpro Bound to A LYS48-Linked Di-Ubiquitin Activity Based Probe, PDB code: 5e6j:

Nickel binding site 1 out of 1 in the Structure of Sars Plpro Bound to A LYS48-Linked Di-Ubiquitin Activity Based Probe


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 1 of Structure of Sars Plpro Bound to A LYS48-Linked Di-Ubiquitin Activity Based Probe within 5.0Å range: probe atom residue distance (Å) B Occ A:Ni402 b:90.5 occ:1.00 NE2 A:HIS192 2.0 0.1 1.0 NE2 A:HIS320 2.0 95.2 1.0 CD2 A:HIS320 2.5 0.3 1.0 CD2 A:HIS192 2.7 0.5 1.0 O A:HOH522 2.9 68.6 1.0 CE1 A:HIS192 3.1 0.1 1.0 CE1 A:HIS320 3.2 92.7 1.0 CG A:HIS320 3.8 0.7 1.0 CG A:HIS192 3.9 0.7 1.0 ND1 A:HIS192 4.0 0.7 1.0 ND1 A:HIS320 4.1 93.3 1.0 O A:LYS191 4.8 0.9 1.0

M.Bekes, G.J.Van Der Heden Van Noort, R.Ekkebus, H.Ovaa, T.T.Huang, C.D.Lima. Recognition of LYS48-Linked Di-Ubiquitin and Deubiquitinating Activities of the Sars Coronavirus Papain-Like Protease. Mol. Cell V. 62 572 2016.
ISSN: ISSN 1097-4164
PubMed: 27203180
DOI: 10.1016/J.MOLCEL.2016.04.016