Nickel in PDB 5gp1: Crystal Structure of Zikv NS5 Methyltransferase in Complex with Gtp and Sah

The structure of Crystal Structure of Zikv NS5 Methyltransferase in Complex with Gtp and Sah, PDB code: 5gp1 was solved by C.Zhang, T.Jin, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.89 / 2.44
Space group	P 61
Cell size a, b, c (Å), α, β, γ (°)	123.770, 123.770, 119.360, 90.00, 90.00, 120.00
R / Rfree (%)	23.7 / 28

The binding sites of Nickel atom in the Crystal Structure of Zikv NS5 Methyltransferase in Complex with Gtp and Sah (pdb code 5gp1). This binding sites where shown within 5.0 Angstroms radius around Nickel atom.
In total only one binding site of Nickel was determined in the Crystal Structure of Zikv NS5 Methyltransferase in Complex with Gtp and Sah, PDB code: 5gp1:

Nickel binding site 1 out of 1 in the Crystal Structure of Zikv NS5 Methyltransferase in Complex with Gtp and Sah


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 1 of Crystal Structure of Zikv NS5 Methyltransferase in Complex with Gtp and Sah within 5.0Å range: probe atom residue distance (Å) B Occ C:Ni302 b:77.8 occ:1.00 CD2 C:HIS110 2.5 46.6 1.0 OE1 C:GLU111 3.0 57.6 1.0 NE2 C:HIS110 3.5 47.7 1.0 OE2 C:GLU111 3.5 60.0 1.0 CD C:GLU111 3.5 58.3 1.0 CG C:HIS110 3.5 49.2 1.0 C3' C:SAH304 3.8 35.2 1.0 O3' C:SAH304 3.9 39.8 1.0 CB C:HIS110 4.0 49.4 1.0 O2' C:SAH304 4.0 39.1 1.0 C2' C:SAH304 4.0 28.0 1.0 CA C:HIS110 4.0 47.4 1.0 O C:GLY109 4.4 42.4 1.0 N C:GLU111 4.4 42.5 1.0 CE1 C:HIS110 4.6 46.8 1.0 ND1 C:HIS110 4.6 48.2 1.0 C C:HIS110 4.7 42.5 1.0 CG C:GLU111 4.7 55.0 1.0

C.Zhang, T.Feng, J.Cheng, Y.Li, X.Yin, W.Zeng, X.Jin, Y.Li, F.Guo, T.Jin. Structure of the NS5 Methyltransferase From Zika Virus and Implications in Inhibitor Design Biochem. Biophys. Res. V. 492 624 2017COMMUN..
ISSN: ESSN 1090-2104
PubMed: 27866982
DOI: 10.1016/J.BBRC.2016.11.098