Nickel in PDB 6dwg: Crystal Structure of Leishmania Major Dihydroorotate Dehydrogenase Mutant Q139A

All present enzymatic activity of Crystal Structure of Leishmania Major Dihydroorotate Dehydrogenase Mutant Q139A:
1.3.98.1;

The structure of Crystal Structure of Leishmania Major Dihydroorotate Dehydrogenase Mutant Q139A, PDB code: 6dwg was solved by R.A.G.Reis, M.P.Pinheiro, M.C.Nonato, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.96 / 1.90
Space group	P 61
Cell size a, b, c (Å), α, β, γ (°)	143.469, 143.469, 69.737, 90.00, 90.00, 120.00
R / Rfree (%)	17.4 / 19.5

The binding sites of Nickel atom in the Crystal Structure of Leishmania Major Dihydroorotate Dehydrogenase Mutant Q139A (pdb code 6dwg). This binding sites where shown within 5.0 Angstroms radius around Nickel atom.
In total only one binding site of Nickel was determined in the Crystal Structure of Leishmania Major Dihydroorotate Dehydrogenase Mutant Q139A, PDB code: 6dwg:

Nickel binding site 1 out of 1 in the Crystal Structure of Leishmania Major Dihydroorotate Dehydrogenase Mutant Q139A


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 1 of Crystal Structure of Leishmania Major Dihydroorotate Dehydrogenase Mutant Q139A within 5.0Å range: probe atom residue distance (Å) B Occ A:Ni406 b:69.8 occ:0.70 O A:HOH640 3.0 43.2 1.0 NE2 A:HIS174 3.3 32.9 0.7 O B:HOH657 3.3 51.5 1.0 NE2 B:HIS174 3.8 28.0 0.7 CD2 A:HIS174 4.1 34.3 0.7 O A:TYR142 4.1 36.7 1.0 NE2 A:HIS174 4.3 19.5 0.3 CE1 A:HIS174 4.3 32.6 0.7 CE1 A:HIS174 4.4 22.1 0.3 NE2 B:HIS174 4.5 19.9 0.3 CE1 B:HIS174 4.5 20.5 0.3 O A:HOH636 4.5 38.8 1.0 CE1 B:HIS174 4.6 30.3 0.7 O B:TYR142 4.7 39.5 1.0 CD2 B:HIS174 4.8 26.7 0.7

R.A.G.Reis, M.P.Pinheiro, M.C.Nonato. Crystal Structure of Leishmania Major Dihydroorotate Dehydrogenase Mutant Q139A To Be Published.