Nickel in PDB 6eak: Crystal Structure of Fusion Inhibitor Jnj-2408068 in Complex with Human Respiratory Syncytial Virus Fusion Glycoprotein Escape Variant T400A Stabilized in the Prefusion State

The structure of Crystal Structure of Fusion Inhibitor Jnj-2408068 in Complex with Human Respiratory Syncytial Virus Fusion Glycoprotein Escape Variant T400A Stabilized in the Prefusion State, PDB code: 6eak was solved by M.B.Battles, J.S.Mclellan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	59.56 / 2.60
Space group	P 41 3 2
Cell size a, b, c (Å), α, β, γ (°)	168.450, 168.450, 168.450, 90.00, 90.00, 90.00
R / Rfree (%)	19.1 / 22.1

The binding sites of Nickel atom in the Crystal Structure of Fusion Inhibitor Jnj-2408068 in Complex with Human Respiratory Syncytial Virus Fusion Glycoprotein Escape Variant T400A Stabilized in the Prefusion State (pdb code 6eak). This binding sites where shown within 5.0 Angstroms radius around Nickel atom.
In total only one binding site of Nickel was determined in the Crystal Structure of Fusion Inhibitor Jnj-2408068 in Complex with Human Respiratory Syncytial Virus Fusion Glycoprotein Escape Variant T400A Stabilized in the Prefusion State, PDB code: 6eak:

Nickel binding site 1 out of 1 in the Crystal Structure of Fusion Inhibitor Jnj-2408068 in Complex with Human Respiratory Syncytial Virus Fusion Glycoprotein Escape Variant T400A Stabilized in the Prefusion State


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 1 of Crystal Structure of Fusion Inhibitor Jnj-2408068 in Complex with Human Respiratory Syncytial Virus Fusion Glycoprotein Escape Variant T400A Stabilized in the Prefusion State within 5.0Å range: probe atom residue distance (Å) B Occ F:Ni608 b:81.0 occ:1.00 N F:TYR458 3.3 33.7 1.0 O F:HOH724 3.4 38.8 1.0 CD1 F:TYR458 3.6 31.3 1.0 CB F:TYR458 3.8 29.3 1.0 CA F:TYR458 4.1 38.0 1.0 O F:LEU456 4.2 46.4 1.0 CA F:TYR457 4.2 33.4 1.0 CG F:TYR458 4.2 43.5 1.0 C F:TYR457 4.2 38.0 1.0 O F:TYR458 4.5 39.6 1.0 CE1 F:TYR458 4.7 44.0 1.0 C F:TYR458 4.8 41.1 1.0

M.B.Battles, J.S.Mclellan. Structural Basis For Respiratory Syncytial Virus Fusion Inhibitor Resistance To Be Published.