Nickel in PDB 6g3x: Native Structure of the Mouse 8-Oxoguanine Dna Glycosylase MOGG1

All present enzymatic activity of Native Structure of the Mouse 8-Oxoguanine Dna Glycosylase MOGG1:
4.2.99.18;

The structure of Native Structure of the Mouse 8-Oxoguanine Dna Glycosylase MOGG1, PDB code: 6g3x was solved by G.Masuyer, T.Helleday, P.Stenmark, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	83.77 / 2.10
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	80.769, 81.213, 167.531, 90.00, 90.00, 90.00
R / Rfree (%)	22.1 / 27.4

The binding sites of Nickel atom in the Native Structure of the Mouse 8-Oxoguanine Dna Glycosylase MOGG1 (pdb code 6g3x). This binding sites where shown within 5.0 Angstroms radius around Nickel atom.
In total only one binding site of Nickel was determined in the Native Structure of the Mouse 8-Oxoguanine Dna Glycosylase MOGG1, PDB code: 6g3x:

Nickel binding site 1 out of 1 in the Native Structure of the Mouse 8-Oxoguanine Dna Glycosylase MOGG1


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 1 of Native Structure of the Mouse 8-Oxoguanine Dna Glycosylase MOGG1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ni401 b:31.9 occ:1.00 NE2 A:HIS282 2.1 31.2 1.0 NE2 C:HIS282 2.2 31.6 1.0 NE2 C:HIS276 2.2 29.8 1.0 NE2 B:HIS276 2.2 28.6 1.0 NE2 A:HIS276 2.2 36.4 1.0 NE2 B:HIS282 2.2 30.2 1.0 CE1 A:HIS282 3.1 31.2 1.0 CE1 C:HIS282 3.1 32.1 1.0 CE1 A:HIS276 3.1 35.9 1.0 CD2 C:HIS276 3.1 29.9 1.0 CE1 B:HIS276 3.2 29.2 1.0 CD2 A:HIS282 3.2 31.4 1.0 CE1 B:HIS282 3.2 30.6 1.0 CD2 B:HIS276 3.2 28.2 1.0 CD2 C:HIS282 3.2 31.3 1.0 CE1 C:HIS276 3.2 29.8 1.0 CD2 A:HIS276 3.2 35.6 1.0 CD2 B:HIS282 3.2 30.2 1.0 ND1 A:HIS282 4.2 32.0 1.0 ND1 C:HIS282 4.2 30.5 1.0 ND1 A:HIS276 4.3 35.5 1.0 ND1 B:HIS276 4.3 28.7 1.0 CG A:HIS282 4.3 32.5 1.0 ND1 C:HIS276 4.3 29.5 1.0 CG C:HIS276 4.3 29.9 1.0 ND1 B:HIS282 4.3 29.1 1.0 CG C:HIS282 4.3 31.8 1.0 CG B:HIS276 4.3 28.8 1.0 CG A:HIS276 4.4 35.6 1.0 CG B:HIS282 4.4 30.8 1.0

T.Visnes, A.Cazares-Korner, W.Hao, O.Wallner, G.Masuyer, O.Loseva, O.Mortusewicz, E.Wiita, A.Sarno, A.Manoilov, J.Astorga-Wells, A.S.Jemth, L.Pan, K.Sanjiv, S.Karsten, C.Gokturk, M.Grube, E.J.Homan, B.M.F.Hanna, C.B.J.Paulin, T.Pham, A.Rasti, U.W.Berglund, C.Von Nicolai, C.Benitez-Buelga, T.Koolmeister, D.Ivanic, P.Iliev, M.Scobie, H.E.Krokan, P.Baranczewski, P.Artursson, M.Altun, A.J.Jensen, C.Kalderen, X.Ba, R.A.Zubarev, P.Stenmark, I.Boldogh, T.Helleday. Small-Molecule Inhibitor of OGG1 Suppresses Proinflammatory Gene Expression and Inflammation. Science V. 362 834 2018.
ISSN: ESSN 1095-9203
PubMed: 30442810
DOI: 10.1126/SCIENCE.AAR8048