Nickel in PDB 6t6j: Crystal Structure of the C-Terminal Domain of the Hiv-1 Integrase (Subtype A2, Mutant N254K, K340Q)

The structure of Crystal Structure of the C-Terminal Domain of the Hiv-1 Integrase (Subtype A2, Mutant N254K, K340Q), PDB code: 6t6j was solved by M.Ruff, M.Negroni, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	41.68 / 2.00
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	85.306, 48.835, 66.749, 90.00, 110.37, 90.00
R / Rfree (%)	16.6 / 22

The binding sites of Nickel atom in the Crystal Structure of the C-Terminal Domain of the Hiv-1 Integrase (Subtype A2, Mutant N254K, K340Q) (pdb code 6t6j). This binding sites where shown within 5.0 Angstroms radius around Nickel atom.
In total 2 binding sites of Nickel where determined in the Crystal Structure of the C-Terminal Domain of the Hiv-1 Integrase (Subtype A2, Mutant N254K, K340Q), PDB code: 6t6j:
Jump to Nickel binding site number: 1; 2;

Nickel binding site 1 out of 2 in the Crystal Structure of the C-Terminal Domain of the Hiv-1 Integrase (Subtype A2, Mutant N254K, K340Q)


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 1 of Crystal Structure of the C-Terminal Domain of the Hiv-1 Integrase (Subtype A2, Mutant N254K, K340Q) within 5.0Å range: probe atom residue distance (Å) B Occ A:Ni301 b:36.3 occ:0.50 HE2 C:HIS214 1.6 73.3 1.0 NE2 A:HIS214 2.2 71.8 1.0 NE2 B:HIS214 2.2 66.5 1.0 NE2 C:HIS214 2.4 61.2 1.0 CE1 A:HIS214 3.0 68.9 1.0 HE1 A:HIS214 3.0 82.6 1.0 CE1 B:HIS214 3.0 68.4 1.0 HE1 B:HIS214 3.0 82.0 1.0 CD2 C:HIS214 3.3 61.0 1.0 CD2 A:HIS214 3.3 71.3 1.0 CD2 B:HIS214 3.4 64.1 1.0 HD2 C:HIS214 3.4 73.1 1.0 CE1 C:HIS214 3.4 66.0 1.0 HE1 C:HIS214 3.6 79.1 1.0 HD2 A:HIS214 3.6 85.4 1.0 HD2 B:HIS214 3.6 76.8 1.0 ND1 A:HIS214 4.2 69.2 1.0 ND1 B:HIS214 4.2 69.0 1.0 CG A:HIS214 4.4 67.4 1.0 CG B:HIS214 4.4 63.4 1.0 CG C:HIS214 4.5 61.7 1.0 ND1 C:HIS214 4.5 65.8 1.0 HD1 A:HIS214 4.9 82.9 1.0 HD1 B:HIS214 4.9 82.7 1.0

Nickel binding site 2 out of 2 in the Crystal Structure of the C-Terminal Domain of the Hiv-1 Integrase (Subtype A2, Mutant N254K, K340Q)


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 2 of Crystal Structure of the C-Terminal Domain of the Hiv-1 Integrase (Subtype A2, Mutant N254K, K340Q) within 5.0Å range: probe atom residue distance (Å) B Occ A:Ni302 b:24.7 occ:1.00 NE2 B:HIS215 2.1 28.9 1.0 NE2 C:HIS215 2.1 23.0 1.0 NE2 A:HIS217 2.2 25.0 1.0 NE2 B:HIS217 2.2 19.7 1.0 NE2 A:HIS215 2.2 22.4 1.0 NE2 C:HIS217 2.2 19.5 1.0 CE1 B:HIS215 3.1 29.7 1.0 CE1 C:HIS215 3.1 24.7 1.0 CD2 B:HIS215 3.1 26.0 1.0 CD2 C:HIS215 3.1 25.5 1.0 CE1 A:HIS217 3.1 25.8 1.0 CD2 C:HIS217 3.1 23.5 1.0 CD2 A:HIS215 3.2 21.7 1.0 CE1 B:HIS217 3.2 19.0 1.0 CD2 B:HIS217 3.2 21.0 1.0 CE1 A:HIS215 3.2 23.0 1.0 HE1 B:HIS215 3.2 35.6 1.0 CD2 A:HIS217 3.2 22.6 1.0 CE1 C:HIS217 3.2 22.8 1.0 HE1 A:HIS217 3.3 30.8 1.0 HE1 C:HIS215 3.3 29.6 1.0 HD2 C:HIS217 3.3 28.1 1.0 HD2 C:HIS215 3.3 30.4 1.0 HD2 A:HIS215 3.3 25.9 1.0 HD2 B:HIS215 3.3 31.1 1.0 HE1 B:HIS217 3.3 22.8 1.0 HD2 B:HIS217 3.3 25.1 1.0 HE1 A:HIS215 3.4 27.6 1.0 HD2 A:HIS217 3.4 27.1 1.0 HE1 C:HIS217 3.4 27.2 1.0 ND1 B:HIS215 4.2 30.7 1.0 ND1 C:HIS215 4.2 25.8 1.0 CG B:HIS215 4.2 28.4 1.0 CG C:HIS215 4.3 26.6 1.0 ND1 A:HIS217 4.3 26.9 1.0 ND1 B:HIS217 4.3 19.6 1.0 HD12 B:ILE257 4.3 34.2 1.0 ND1 A:HIS215 4.3 24.6 1.0 CG C:HIS217 4.3 24.3 1.0 CG A:HIS215 4.3 22.0 1.0 ND1 C:HIS217 4.3 23.3 1.0 CG B:HIS217 4.3 20.6 1.0 CG A:HIS217 4.3 25.6 1.0 HD12 C:ILE257 4.3 29.1 1.0 HD12 A:ILE257 4.4 32.2 1.0 HD1 B:HIS215 5.0 36.8 1.0 HD11 C:ILE257 5.0 29.1 1.0 HD11 B:ILE257 5.0 34.2 1.0 CD1 B:ILE257 5.0 28.6 1.0 HD1 C:HIS215 5.0 30.9 1.0

M.Ruff, M.Negroni. Crystal Structure of the C-Terminal Domain of the Hiv-1 Integrase (Subtype A2, Mutant N254K, K240Q) To Be Published.