Nickel in PDB 7vjs: Human Alkb Homolog ALKBH6 in Complex with Tris and Ni

The structure of Human Alkb Homolog ALKBH6 in Complex with Tris and Ni, PDB code: 7vjs was solved by L.Ma, Z.Chen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.72 / 1.79
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	46.374, 64.212, 88.96, 90, 90, 90
R / Rfree (%)	19.7 / 21.4

The binding sites of Nickel atom in the Human Alkb Homolog ALKBH6 in Complex with Tris and Ni (pdb code 7vjs). This binding sites where shown within 5.0 Angstroms radius around Nickel atom.
In total only one binding site of Nickel was determined in the Human Alkb Homolog ALKBH6 in Complex with Tris and Ni, PDB code: 7vjs:

Nickel binding site 1 out of 1 in the Human Alkb Homolog ALKBH6 in Complex with Tris and Ni


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 1 of Human Alkb Homolog ALKBH6 in Complex with Tris and Ni within 5.0Å range: probe atom residue distance (Å) B Occ A:Ni301 b:20.7 occ:1.00 NE2 A:HIS182 2.0 17.7 1.0 OD2 A:ASP116 2.1 20.4 1.0 O1 A:TRS302 2.1 23.1 1.0 NE2 A:HIS114 2.1 20.7 1.0 O2 A:TRS302 2.2 23.2 1.0 N A:TRS302 2.3 27.1 1.0 C A:TRS302 2.8 25.9 1.0 C1 A:TRS302 3.0 26.5 1.0 C2 A:TRS302 3.0 23.6 1.0 CE1 A:HIS182 3.0 17.6 1.0 CG A:ASP116 3.0 20.6 1.0 CD2 A:HIS182 3.1 18.7 1.0 CD2 A:HIS114 3.1 20.9 1.0 CE1 A:HIS114 3.1 21.6 1.0 OD1 A:ASP116 3.3 22.7 1.0 ND1 A:HIS182 4.1 17.4 1.0 CG A:HIS182 4.2 17.1 1.0 ND1 A:HIS114 4.2 21.8 1.0 CG A:HIS114 4.2 18.7 1.0 C3 A:TRS302 4.3 29.1 1.0 CB A:ASP116 4.4 21.4 1.0 O A:HOH444 4.6 29.6 1.0 CA A:ASP116 4.8 22.5 1.0 O3 A:TRS302 4.9 29.0 1.0 N A:ASP116 5.0 22.8 1.0

L.Ma, H.Lu, Z.Tian, M.Yang, J.Ma, G.Shang, Y.Liu, M.Xie, G.Wang, W.Wu, Z.Zhang, S.Dai, Z.Chen. Structural Insights Into the Interactions and Epigenetic Functions of Human Nucleic Acid Repair Protein ALKBH6. J.Biol.Chem. V. 298 01671 2022.
ISSN: ESSN 1083-351X
PubMed: 35120926
DOI: 10.1016/J.JBC.2022.101671