Nickel in PDB 7zvc: Second Crystal Form of the Mature Glutamic-Class Prolyl-Endopeptidase Neprosin at 1.85 A Resolution.

The structure of Second Crystal Form of the Mature Glutamic-Class Prolyl-Endopeptidase Neprosin at 1.85 A Resolution., PDB code: 7zvc was solved by A.Rodriguez-Banqueri, U.Eckhard, L.Del Amo-Maestro, S.R.Mendes, T.Guevara, F.X.Gomis-Ruth, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.66 / 1.85
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	58.86, 40.63, 64.63, 90, 107.98, 90
R / Rfree (%)	17.3 / 20.3

The binding sites of Nickel atom in the Second Crystal Form of the Mature Glutamic-Class Prolyl-Endopeptidase Neprosin at 1.85 A Resolution. (pdb code 7zvc). This binding sites where shown within 5.0 Angstroms radius around Nickel atom.
In total only one binding site of Nickel was determined in the Second Crystal Form of the Mature Glutamic-Class Prolyl-Endopeptidase Neprosin at 1.85 A Resolution., PDB code: 7zvc:

Nickel binding site 1 out of 1 in the Second Crystal Form of the Mature Glutamic-Class Prolyl-Endopeptidase Neprosin at 1.85 A Resolution.


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 1 of Second Crystal Form of the Mature Glutamic-Class Prolyl-Endopeptidase Neprosin at 1.85 A Resolution. within 5.0Å range: probe atom residue distance (Å) B Occ A:Ni505 b:31.7 occ:0.46 NE2 A:HIS405 1.8 44.1 1.0 O4 A:SO4502 2.7 68.5 0.7 CE1 A:HIS405 2.8 44.2 1.0 CD2 A:HIS405 2.9 42.6 1.0 O1 A:SO4502 2.9 68.2 0.7 S A:SO4502 3.2 68.7 0.7 O2 A:SO4502 3.5 68.7 0.7 ND1 A:HIS405 3.9 43.5 1.0 CG A:HIS405 4.0 40.6 1.0 O A:HIS406 4.0 36.0 1.0 CA A:HIS407 4.1 41.1 1.0 O A:HOH696 4.2 39.6 1.0 C A:HIS406 4.4 36.2 1.0 N A:HIS407 4.4 38.3 1.0 O3 A:SO4502 4.6 68.8 0.7 CB A:HIS407 4.8 43.2 1.0

L.Del Amo-Maestro, S.R.Mendes, A.Rodriguez-Banqueri, L.Garzon-Flores, M.Girbal, M.J.Rodriguez-Lagunas, T.Guevara, A.Franch, F.J.Perez-Cano, U.Eckhard, F.X.Gomis-Ruth. Molecular and in Vivo Studies of A Glutamate-Class Prolyl-Endopeptidase For Coeliac Disease Therapy. Nat Commun V. 13 4446 2022.
ISSN: ESSN 2041-1723
PubMed: 35915115
DOI: 10.1038/S41467-022-32215-1