Nickel in PDB 8avc: Mouse Leptin:Lep-R Complex Cryoem Structure (3:3 Model)

The binding sites of Nickel atom in the Mouse Leptin:Lep-R Complex Cryoem Structure (3:3 Model) (pdb code 8avc). This binding sites where shown within 5.0 Angstroms radius around Nickel atom.
In total 3 binding sites of Nickel where determined in the Mouse Leptin:Lep-R Complex Cryoem Structure (3:3 Model), PDB code: 8avc:
Jump to Nickel binding site number: 1; 2; 3;

Nickel binding site 1 out of 3 in the Mouse Leptin:Lep-R Complex Cryoem Structure (3:3 Model)


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 1 of Mouse Leptin:Lep-R Complex Cryoem Structure (3:3 Model) within 5.0Å range: probe atom residue distance (Å) B Occ B:Ni901 b:190.0 occ:1.00 NH1 B:ARG467 2.0 190.0 1.0 CD B:ARG467 2.5 190.0 1.0 CE1 B:HIS478 2.6 190.0 1.0 NE2 B:HIS478 2.8 190.0 1.0 CZ B:ARG467 2.9 190.0 1.0 NE B:ARG467 3.0 190.0 1.0 ND1 B:HIS478 3.1 190.0 1.0 CD2 B:HIS478 3.5 190.0 1.0 CG B:HIS478 3.6 190.0 1.0 CG B:ARG467 3.9 190.0 1.0 NH2 B:ARG467 4.1 190.0 1.0 CB B:HIS478 4.8 190.0 1.0 CB B:ARG467 4.9 190.0 1.0 NE2 B:HIS465 5.0 190.0 1.0

Nickel binding site 2 out of 3 in the Mouse Leptin:Lep-R Complex Cryoem Structure (3:3 Model)


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 2 of Mouse Leptin:Lep-R Complex Cryoem Structure (3:3 Model) within 5.0Å range: probe atom residue distance (Å) B Occ D:Ni901 b:190.0 occ:1.00 NE2 D:HIS478 3.7 190.0 1.0 CD2 D:HIS478 3.9 190.0 1.0 NE D:ARG467 4.6 190.0 1.0 CD D:ARG467 4.7 190.0 1.0 CE1 D:HIS478 4.8 190.0 1.0 CG D:ARG467 4.9 190.0 1.0

Nickel binding site 3 out of 3 in the Mouse Leptin:Lep-R Complex Cryoem Structure (3:3 Model)


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 3 of Mouse Leptin:Lep-R Complex Cryoem Structure (3:3 Model) within 5.0Å range: probe atom residue distance (Å) B Occ F:Ni901 b:93.5 occ:1.00 CZ F:ARG467 2.2 190.0 1.0 NH2 F:ARG467 2.4 190.0 1.0 NH1 F:ARG467 2.6 190.0 1.0 NE F:ARG467 2.8 190.0 1.0 CE1 F:HIS478 3.0 190.0 1.0 CD F:ARG467 3.6 190.0 1.0 NE2 F:HIS478 3.7 190.0 1.0 ND1 F:HIS478 4.1 190.0 1.0 CG F:ARG467 4.7 190.0 1.0 CD2 F:HIS478 5.0 190.0 1.0

A.Tsirigotaki, A.Dansercoer, K.H.G.Verschueren, I.Markovic, C.Pollmann, M.Hafer, J.Felix, C.Birck, W.Van Putte, D.Catteeuw, J.Tavernier, J.Fernando Bazan, J.Piehler, S.N.Savvides, K.Verstraete. Mechanism of Receptor Assembly Via the Pleiotropic Adipokine Leptin. Nat.Struct.Mol.Biol. 2023.
ISSN: ESSN 1545-9985
PubMed: 36959263
DOI: 10.1038/S41594-023-00941-9