Nickel in PDB 8avd: Cryo-Em Structure For A 3:3 Complex Between Mouse Leptin and the Mouse Lep-R Ectodomain (Local Refinement)

The binding sites of Nickel atom in the Cryo-Em Structure For A 3:3 Complex Between Mouse Leptin and the Mouse Lep-R Ectodomain (Local Refinement) (pdb code 8avd). This binding sites where shown within 5.0 Angstroms radius around Nickel atom.
In total 3 binding sites of Nickel where determined in the Cryo-Em Structure For A 3:3 Complex Between Mouse Leptin and the Mouse Lep-R Ectodomain (Local Refinement), PDB code: 8avd:
Jump to Nickel binding site number: 1; 2; 3;

Nickel binding site 1 out of 3 in the Cryo-Em Structure For A 3:3 Complex Between Mouse Leptin and the Mouse Lep-R Ectodomain (Local Refinement)


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 1 of Cryo-Em Structure For A 3:3 Complex Between Mouse Leptin and the Mouse Lep-R Ectodomain (Local Refinement) within 5.0Å range: probe atom residue distance (Å) B Occ B:Ni901 b:179.7 occ:1.00 NH2 B:ARG467 3.5 179.7 1.0 NE B:ARG467 3.6 179.7 1.0 CZ B:ARG467 3.7 179.7 1.0 CD B:ARG467 4.5 179.7 1.0 NH1 B:ARG467 4.5 179.7 1.0 NE2 B:HIS478 4.6 179.7 1.0 CG B:ARG467 4.9 179.7 1.0

Nickel binding site 2 out of 3 in the Cryo-Em Structure For A 3:3 Complex Between Mouse Leptin and the Mouse Lep-R Ectodomain (Local Refinement)


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 2 of Cryo-Em Structure For A 3:3 Complex Between Mouse Leptin and the Mouse Lep-R Ectodomain (Local Refinement) within 5.0Å range: probe atom residue distance (Å) B Occ D:Ni901 b:83.5 occ:1.00 NH2 D:ARG467 3.4 190.7 1.0 NE D:ARG467 3.5 190.7 1.0 CZ D:ARG467 3.5 190.7 1.0 CD D:ARG467 4.3 190.7 1.0 NH1 D:ARG467 4.3 190.7 1.0 CG D:ARG467 4.7 190.7 1.0 NE2 D:HIS478 4.8 189.5 1.0

Nickel binding site 3 out of 3 in the Cryo-Em Structure For A 3:3 Complex Between Mouse Leptin and the Mouse Lep-R Ectodomain (Local Refinement)


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 3 of Cryo-Em Structure For A 3:3 Complex Between Mouse Leptin and the Mouse Lep-R Ectodomain (Local Refinement) within 5.0Å range: probe atom residue distance (Å) B Occ F:Ni901 b:179.7 occ:1.00 CE1 F:HIS478 4.3 179.7 1.0 NH2 F:ARG467 4.3 179.7 1.0 NE F:ARG467 4.4 179.7 1.0 CZ F:ARG467 4.6 179.7 1.0

A.Tsirigotaki, A.Dansercoer, K.H.G.Verschueren, I.Markovic, C.Pollmann, M.Hafer, J.Felix, C.Birck, W.Van Putte, D.Catteeuw, J.Tavernier, J.Fernando Bazan, J.Piehler, S.N.Savvides, K.Verstraete. Mechanism of Receptor Assembly Via the Pleiotropic Adipokine Leptin. Nat.Struct.Mol.Biol. 2023.
ISSN: ESSN 1545-9985
PubMed: 36959263
DOI: 10.1038/S41594-023-00941-9