Nickel in PDB 8bq7: Structure of the Mouse 8-Oxoguanine Dna Glycosylase MOGG1 in Complex with Ligand TH2829

All present enzymatic activity of Structure of the Mouse 8-Oxoguanine Dna Glycosylase MOGG1 in Complex with Ligand TH2829:
4.2.99.18;

The structure of Structure of the Mouse 8-Oxoguanine Dna Glycosylase MOGG1 in Complex with Ligand TH2829, PDB code: 8bq7 was solved by E.Scaletti, P.Stenmark, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	72.99 / 2.60
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	80.733, 82.095, 169.487, 90, 90, 90
R / Rfree (%)	25.5 / 30.7

The binding sites of Nickel atom in the Structure of the Mouse 8-Oxoguanine Dna Glycosylase MOGG1 in Complex with Ligand TH2829 (pdb code 8bq7). This binding sites where shown within 5.0 Angstroms radius around Nickel atom.
In total only one binding site of Nickel was determined in the Structure of the Mouse 8-Oxoguanine Dna Glycosylase MOGG1 in Complex with Ligand TH2829, PDB code: 8bq7:

Nickel binding site 1 out of 1 in the Structure of the Mouse 8-Oxoguanine Dna Glycosylase MOGG1 in Complex with Ligand TH2829


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 1 of Structure of the Mouse 8-Oxoguanine Dna Glycosylase MOGG1 in Complex with Ligand TH2829 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ni402 b:56.1 occ:1.00 NE2 B:HIS276 2.1 57.1 1.0 NE2 A:HIS276 2.2 58.8 1.0 NE2 A:HIS282 2.2 49.4 1.0 NE2 C:HIS276 2.2 55.0 1.0 NE2 B:HIS282 2.3 59.4 1.0 NE2 C:HIS282 2.3 53.7 1.0 CE1 B:HIS276 3.0 57.7 1.0 CE1 C:HIS276 3.1 54.8 1.0 CE1 A:HIS276 3.1 56.9 1.0 CE1 A:HIS282 3.1 49.9 1.0 CE1 C:HIS282 3.2 54.7 1.0 CD2 B:HIS282 3.2 58.2 1.0 CD2 B:HIS276 3.2 57.5 1.0 CD2 A:HIS276 3.2 58.9 1.0 CD2 A:HIS282 3.3 49.0 1.0 CD2 C:HIS276 3.3 55.2 1.0 CE1 B:HIS282 3.3 57.9 1.0 CD2 C:HIS282 3.3 55.6 1.0 ND1 B:HIS276 4.2 55.9 1.0 ND1 A:HIS276 4.2 58.3 1.0 ND1 C:HIS276 4.2 53.2 1.0 ND1 A:HIS282 4.3 48.5 1.0 CG B:HIS276 4.3 55.9 1.0 CG A:HIS276 4.3 59.1 1.0 ND1 C:HIS282 4.3 55.5 1.0 CG B:HIS282 4.3 58.0 1.0 CG C:HIS276 4.3 55.1 1.0 CG A:HIS282 4.4 48.8 1.0 ND1 B:HIS282 4.4 57.7 1.0 CG C:HIS282 4.4 56.2 1.0

E.Scaletti, P.Stenmark. Structure of the Mouse 8-Oxoguanine Dna Glycosylase MOGG1 in Complex with Ligand TH2829 To Be Published.