Atomistry » Nickel » PDB 2gw4-2pos » 2ok3
Atomistry »
  Nickel »
    PDB 2gw4-2pos »
      2ok3 »

Nickel in PDB 2ok3: X-Ray Structure of Human Cyclophilin J at 2.0 Angstrom

Enzymatic activity of X-Ray Structure of Human Cyclophilin J at 2.0 Angstrom

All present enzymatic activity of X-Ray Structure of Human Cyclophilin J at 2.0 Angstrom:
5.2.1.8;

Protein crystallography data

The structure of X-Ray Structure of Human Cyclophilin J at 2.0 Angstrom, PDB code: 2ok3 was solved by Z.Xia, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 22.11 / 2.00
Space group P 31 2 1
Cell size a, b, c (Å), α, β, γ (°) 40.577, 40.577, 170.682, 90.00, 90.00, 120.00
R / Rfree (%) 20.2 / 25.5

Nickel Binding Sites:

The binding sites of Nickel atom in the X-Ray Structure of Human Cyclophilin J at 2.0 Angstrom (pdb code 2ok3). This binding sites where shown within 5.0 Angstroms radius around Nickel atom.
In total 2 binding sites of Nickel where determined in the X-Ray Structure of Human Cyclophilin J at 2.0 Angstrom, PDB code: 2ok3:
Jump to Nickel binding site number: 1; 2;

Nickel binding site 1 out of 2 in 2ok3

Go back to Nickel Binding Sites List in 2ok3
Nickel binding site 1 out of 2 in the X-Ray Structure of Human Cyclophilin J at 2.0 Angstrom


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 1 of X-Ray Structure of Human Cyclophilin J at 2.0 Angstrom within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ni801

b:55.0
occ:1.00
O A:HOH948 2.1 38.0 1.0
O A:HOH936 2.2 42.6 1.0
ND1 A:HIS6 2.4 34.8 1.0
O A:HOH955 2.7 43.2 1.0
O A:HOH961 2.8 44.5 1.0
CG A:HIS6 3.3 33.6 1.0
CE1 A:HIS6 3.3 35.4 1.0
O A:HOH953 3.4 50.2 1.0
CB A:HIS6 3.6 31.6 1.0
OD1 A:ASP11 4.0 32.1 1.0
OD2 A:ASP11 4.0 34.0 1.0
CG A:ASP11 4.4 32.7 1.0
NE2 A:HIS6 4.4 35.7 1.0
CD2 A:HIS6 4.5 34.7 1.0
CA A:HIS6 4.7 31.2 1.0
OD1 A:ASP151 4.7 40.7 1.0

Nickel binding site 2 out of 2 in 2ok3

Go back to Nickel Binding Sites List in 2ok3
Nickel binding site 2 out of 2 in the X-Ray Structure of Human Cyclophilin J at 2.0 Angstrom


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 2 of X-Ray Structure of Human Cyclophilin J at 2.0 Angstrom within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ni802

b:44.5
occ:1.00
O A:HOH940 2.0 34.4 1.0
NE2 A:HIS148 2.1 32.2 1.0
O A:HOH938 2.3 35.1 1.0
O A:HOH939 2.3 40.0 1.0
O A:HOH937 2.5 43.5 1.0
CD2 A:HIS148 3.0 30.0 1.0
CE1 A:HIS148 3.1 32.0 1.0
OD2 A:ASP146 4.0 34.8 1.0
O A:HOH867 4.0 33.9 1.0
O A:HOH922 4.1 44.6 1.0
CG A:HIS148 4.1 30.5 1.0
ND1 A:HIS148 4.2 31.5 1.0
CB A:ASP146 4.5 31.7 1.0
CG A:ASP146 4.7 33.6 1.0
CG2 A:ILE41 4.7 24.0 1.0

Reference:

J.Chen, S.Chen, L.Huang, X.Zhao, J.Tan, C.Huang, H.Saiyin, M.Zhang, X.Zeng, J.Xi, B.Wan, Y.Zhao, Z.Xia, H.Jiang, Q.Yi, J.O.Liu, L.Yu. Targeting Cyclophilin J, A Novel Peptidyl-Prolyl Isomerase, Can Induce Cellular G1/S Arrest and Repress the Growth of Hepatocellular Carcinoma To Be Published.
Page generated: Wed Oct 9 16:52:56 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy