Nickel in PDB 2qnk: Crystal Structure of Human 3-Hydroxyanthranilate 3,4-Dioxygenase

All present enzymatic activity of Crystal Structure of Human 3-Hydroxyanthranilate 3,4-Dioxygenase:
1.13.11.6;

The structure of Crystal Structure of Human 3-Hydroxyanthranilate 3,4-Dioxygenase, PDB code: 2qnk was solved by E.Bitto, C.A.Bingman, G.E.Wesenberg, G.N.Phillips Jr., Center Foreukaryotic Structural Genomics (Cesg), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.92 / 1.60
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	50.498, 78.227, 85.080, 90.00, 90.00, 90.00
R / Rfree (%)	15.7 / 17.6

The binding sites of Nickel atom in the Crystal Structure of Human 3-Hydroxyanthranilate 3,4-Dioxygenase (pdb code 2qnk). This binding sites where shown within 5.0 Angstroms radius around Nickel atom.
In total only one binding site of Nickel was determined in the Crystal Structure of Human 3-Hydroxyanthranilate 3,4-Dioxygenase, PDB code: 2qnk:

Nickel binding site 1 out of 1 in the Crystal Structure of Human 3-Hydroxyanthranilate 3,4-Dioxygenase


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 1 of Crystal Structure of Human 3-Hydroxyanthranilate 3,4-Dioxygenase within 5.0Å range: probe atom residue distance (Å) B Occ A:Ni287 b:4.6 occ:1.00 O A:HOH289 2.1 7.0 1.0 NE2 A:HIS91 2.1 14.9 1.0 O A:HOH290 2.1 5.3 1.0 ND1 A:HIS47 2.1 14.2 1.0 OE2 A:GLU53 2.2 16.5 1.0 OE1 A:GLU53 2.2 15.3 1.0 CD A:GLU53 2.6 14.8 1.0 CE1 A:HIS47 2.9 15.8 1.0 CE1 A:HIS91 3.0 15.3 1.0 CD2 A:HIS91 3.1 16.4 1.0 CG A:HIS47 3.3 16.8 1.0 O A:HOH305 3.7 9.2 1.0 CB A:HIS47 3.8 14.6 1.0 CG A:GLU53 4.1 14.2 1.0 NE2 A:HIS47 4.1 15.8 1.0 ND1 A:HIS91 4.2 14.5 1.0 OE1 A:GLU105 4.2 14.7 1.0 CG A:HIS91 4.2 15.4 1.0 CD2 A:HIS47 4.3 15.9 1.0 O A:HOH298 4.3 11.4 1.0 OE2 A:GLU49 4.5 14.8 1.0 O A:HOH448 4.6 20.9 1.0 CD2 A:LEU137 4.8 25.5 1.0 CG A:GLU49 4.9 14.8 1.0

E.Bitto, C.A.Bingman, G.E.Wesenberg, G.N.Phillips Jr.. Crystal Structure of Human 3-Hydroxyanthranilate 3,4-Dioxygenase. To Be Published.