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Atomistry » Nickel » PDB 6cac-6f5r » 6dw5 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Nickel » PDB 6cac-6f5r » 6dw5 » |
Nickel in PDB 6dw5: SAMHD1 Bound to Gemcitabine-Tp in the Catalytic PocketProtein crystallography data
The structure of SAMHD1 Bound to Gemcitabine-Tp in the Catalytic Pocket, PDB code: 6dw5
was solved by
K.M.Knecht,
O.Buzovetsky,
C.Schneider,
D.Thomas,
V.Srikanth,
L.Kaderali,
F.Tofoleanu,
K.Reiss,
N.Ferreiros,
G.Geisslinger,
V.S.Batista,
X.Ji,
J.Cinatl,
O.T.Keppler,
Y.Xiong,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6dw5:
The structure of SAMHD1 Bound to Gemcitabine-Tp in the Catalytic Pocket also contains other interesting chemical elements:
Nickel Binding Sites:
The binding sites of Nickel atom in the SAMHD1 Bound to Gemcitabine-Tp in the Catalytic Pocket
(pdb code 6dw5). This binding sites where shown within
5.0 Angstroms radius around Nickel atom.
In total only one binding site of Nickel was determined in the SAMHD1 Bound to Gemcitabine-Tp in the Catalytic Pocket, PDB code: 6dw5: Nickel binding site 1 out of 1 in 6dw5Go back to![]() ![]()
Nickel binding site 1 out
of 1 in the SAMHD1 Bound to Gemcitabine-Tp in the Catalytic Pocket
![]() Mono view ![]() Stereo pair view
Reference:
K.M.Knecht,
O.Buzovetsky,
C.Schneider,
D.Thomas,
V.Srikanth,
L.Kaderali,
F.Tofoleanu,
K.Reiss,
N.Ferreiros,
G.Geisslinger,
V.S.Batista,
X.Ji,
J.Cinatl Jr.,
O.T.Keppler,
Y.Xiong.
The Structural Basis For Cancer Drug Interactions with the Catalytic and Allosteric Sites of SAMHD1. Proc. Natl. Acad. Sci. V. 115 10022 2018U.S.A..
Page generated: Thu Oct 10 08:22:25 2024
ISSN: ESSN 1091-6490 PubMed: 30305425 DOI: 10.1073/PNAS.1805593115 |
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