Atomistry » Nickel » PDB 1fwc-1j6p » 1kie
Atomistry »
  Nickel »
    PDB 1fwc-1j6p »
      1kie »

Nickel in PDB 1kie: Inosine-Adenosine-Guanosine Preferring Nucleoside Hydrolase From Trypanosoma Vivax: ASP10ALA Mutant in Complex with 3- Deaza-Adenosine

Enzymatic activity of Inosine-Adenosine-Guanosine Preferring Nucleoside Hydrolase From Trypanosoma Vivax: ASP10ALA Mutant in Complex with 3- Deaza-Adenosine

All present enzymatic activity of Inosine-Adenosine-Guanosine Preferring Nucleoside Hydrolase From Trypanosoma Vivax: ASP10ALA Mutant in Complex with 3- Deaza-Adenosine:
3.2.2.1;

Protein crystallography data

The structure of Inosine-Adenosine-Guanosine Preferring Nucleoside Hydrolase From Trypanosoma Vivax: ASP10ALA Mutant in Complex with 3- Deaza-Adenosine, PDB code: 1kie was solved by W.Versees, K.Decanniere, E.Van Holsbeke, N.Devroede, J.Steyaert, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 20.00 / 2.00
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 53.270, 72.960, 71.530, 90.00, 98.18, 90.00
R / Rfree (%) 15.6 / 21.5

Nickel Binding Sites:

The binding sites of Nickel atom in the Inosine-Adenosine-Guanosine Preferring Nucleoside Hydrolase From Trypanosoma Vivax: ASP10ALA Mutant in Complex with 3- Deaza-Adenosine (pdb code 1kie). This binding sites where shown within 5.0 Angstroms radius around Nickel atom.
In total only one binding site of Nickel was determined in the Inosine-Adenosine-Guanosine Preferring Nucleoside Hydrolase From Trypanosoma Vivax: ASP10ALA Mutant in Complex with 3- Deaza-Adenosine, PDB code: 1kie:

Nickel binding site 1 out of 1 in 1kie

Go back to Nickel Binding Sites List in 1kie
Nickel binding site 1 out of 1 in the Inosine-Adenosine-Guanosine Preferring Nucleoside Hydrolase From Trypanosoma Vivax: ASP10ALA Mutant in Complex with 3- Deaza-Adenosine


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 1 of Inosine-Adenosine-Guanosine Preferring Nucleoside Hydrolase From Trypanosoma Vivax: ASP10ALA Mutant in Complex with 3- Deaza-Adenosine within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ni701

b:20.0
occ:1.00
OE2 A:GLU113 1.9 22.0 1.0
OE2 A:GLU44 2.0 18.7 1.0
O A:HOH957 2.1 17.3 1.0
CD A:GLU113 2.7 19.0 1.0
CD A:GLU44 2.8 18.3 1.0
OE1 A:GLU113 3.0 19.1 1.0
OE1 A:GLU44 3.0 17.0 1.0
O A:HOH813 3.7 17.9 1.0
O A:HOH962 3.8 24.9 1.0
CG A:GLU113 4.1 19.7 1.0
CG A:GLU44 4.2 17.6 1.0
CE A:LYS70 4.3 20.3 1.0
CE A:LYS109 4.4 21.2 1.0
CE2 A:PHE47 4.6 18.6 1.0
O A:HOH814 4.8 18.5 1.0
CD2 A:PHE47 4.8 20.6 1.0
NZ A:LYS109 5.0 20.5 1.0
NZ A:LYS70 5.0 24.9 1.0

Reference:

W.Versees, K.Decanniere, E.Van Holsbeke, N.Devroede, J.Steyaert. Enzyme-Substrate Interactions in the Purine-Specific Nucleoside Hydrolase From Trypanosoma Vivax. J.Biol.Chem. V. 277 15938 2002.
ISSN: ISSN 0021-9258
PubMed: 11854281
DOI: 10.1074/JBC.M111735200
Page generated: Fri Sep 25 07:56:32 2020
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy