Nickel in PDB 3iar: The Crystal Structure of Human Adenosine Deaminase

All present enzymatic activity of The Crystal Structure of Human Adenosine Deaminase:
3.5.4.4;

The structure of The Crystal Structure of Human Adenosine Deaminase, PDB code: 3iar was solved by E.Ugochukwu, Y.Zhang, E.Hapka, W.W.Yue, J.E.Bray, J.Muniz, N.Burgess-Brown, A.Chaikuad, F.Von Delft, C.Bountra, C.H.Arrowsmith, J.Weigelt, A.Edwards, K.L.Kavanagh, U.Oppermann, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.70 / 1.52
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	61.070, 73.510, 76.660, 90.00, 90.00, 90.00
R / Rfree (%)	15.3 / 18.5

The binding sites of Nickel atom in the The Crystal Structure of Human Adenosine Deaminase (pdb code 3iar). This binding sites where shown within 5.0 Angstroms radius around Nickel atom.
In total only one binding site of Nickel was determined in the The Crystal Structure of Human Adenosine Deaminase, PDB code: 3iar:

Nickel binding site 1 out of 1 in the The Crystal Structure of Human Adenosine Deaminase


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 1 of The Crystal Structure of Human Adenosine Deaminase within 5.0Å range: probe atom residue distance (Å) B Occ A:Ni1 b:8.4 occ:1.00 NE2 A:HIS17 2.0 7.2 1.0 NE2 A:HIS15 2.1 8.7 1.0 OD1 A:ASP295 2.1 7.2 1.0 N6 A:3D1501 2.2 5.8 1.0 NE2 A:HIS214 2.2 9.0 1.0 C6 A:3D1501 2.8 12.4 1.0 CD2 A:HIS17 3.0 8.1 1.0 CD2 A:HIS15 3.1 5.7 1.0 CE1 A:HIS17 3.1 6.5 1.0 CE1 A:HIS15 3.1 5.9 1.0 CG A:ASP295 3.2 7.7 1.0 CD2 A:HIS214 3.2 8.8 1.0 CE1 A:HIS214 3.2 7.9 1.0 C5 A:3D1501 3.2 12.2 1.0 N7 A:3D1501 3.3 11.6 1.0 OD2 A:ASP295 3.5 8.2 1.0 NE2 A:HIS238 3.8 11.3 1.0 N1 A:3D1501 3.9 12.5 1.0 CG A:HIS17 4.1 6.3 1.0 ND1 A:HIS17 4.2 7.5 1.0 ND1 A:HIS15 4.2 7.7 1.0 CG A:HIS15 4.2 6.5 1.0 ND1 A:HIS214 4.3 8.0 1.0 OD2 A:ASP296 4.3 10.8 1.0 CG A:HIS214 4.3 5.4 1.0 C4 A:3D1501 4.4 13.6 1.0 C8 A:3D1501 4.4 8.1 1.0 CB A:ASP295 4.4 6.4 1.0 CD2 A:HIS238 4.5 9.9 1.0 CE1 A:HIS238 4.7 11.3 1.0 O A:HOH781 4.7 18.9 1.0 CA A:ASP295 4.8 6.6 1.0 C2 A:3D1501 4.8 13.8 1.0 CD A:ARG101 4.9 7.4 1.0

E.Ugochukwu, Y.Zhang, E.Hapka, W.W.Yue, J.E.Bray, J.Muniz, N.Burgess-Brown, A.Chaikuad, K.L.Kavanagh, U.Oppermann. The Crystal Structure of Human Adenosine Deaminase To Be Published.