Nickel in PDB 3n6m: Crystal Structure of EV71 Rdrp in Complex with Gtp

The structure of Crystal Structure of EV71 Rdrp in Complex with Gtp, PDB code: 3n6m was solved by Y.Wu, Z.Y.Lou, Y.Miao, Y.Yu, Z.H.Rao, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.50
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	103.494, 103.494, 133.049, 90.00, 90.00, 120.00
R / Rfree (%)	19.4 / 24.9

The binding sites of Nickel atom in the Crystal Structure of EV71 Rdrp in Complex with Gtp (pdb code 3n6m). This binding sites where shown within 5.0 Angstroms radius around Nickel atom.
In total only one binding site of Nickel was determined in the Crystal Structure of EV71 Rdrp in Complex with Gtp, PDB code: 3n6m:

Nickel binding site 1 out of 1 in the Crystal Structure of EV71 Rdrp in Complex with Gtp


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 1 of Crystal Structure of EV71 Rdrp in Complex with Gtp within 5.0Å range: probe atom residue distance (Å) B Occ A:Ni463 b:42.8 occ:1.00 NE2 A:HIS271 2.0 33.1 1.0 NE2 A:HIS273 2.2 40.2 1.0 SG A:CYS282 2.4 35.4 1.0 O A:HOH612 2.7 41.4 1.0 CE1 A:HIS271 3.0 33.5 1.0 CD2 A:HIS273 3.0 39.9 1.0 CD2 A:HIS271 3.1 34.3 1.0 CE1 A:HIS273 3.3 40.1 1.0 CB A:CYS282 3.3 32.2 1.0 ND1 A:HIS271 4.1 34.6 1.0 CG A:HIS271 4.2 33.4 1.0 CG A:HIS273 4.3 39.3 1.0 NE1 A:TRP5 4.3 38.1 1.0 ND1 A:HIS273 4.3 39.3 1.0 CA A:CYS282 4.4 32.4 1.0 CZ2 A:TRP5 4.5 37.7 1.0 CE2 A:TRP5 4.7 37.5 1.0 O A:THR272 4.8 36.0 1.0

Y.Wu, Z.Lou, Y.Miao, Y.Yu, H.Dong, W.Peng, M.Bartlam, X.Li, Z.Rao. Structures of EV71 Rna-Dependent Rna Polymerase in Complex with Substrate and Analogue Provide A Drug Target Against the Hand-Foot-and-Mouth Disease Pandemic in China. Protein Cell V. 1 491 2010.
ISSN: ISSN 1674-800X
PubMed: 21203964
DOI: 10.1007/S13238-010-0061-7