Nickel in PDB 4kng: Crystal Structure of Human LGR5-RSPO1-RNF43

The structure of Crystal Structure of Human LGR5-RSPO1-RNF43, PDB code: 4kng was solved by P.H.Chen, X.He, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.51 / 2.50
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	104.575, 120.971, 181.009, 90.00, 90.00, 90.00
R / Rfree (%)	23.2 / 27.6

The binding sites of Nickel atom in the Crystal Structure of Human LGR5-RSPO1-RNF43 (pdb code 4kng). This binding sites where shown within 5.0 Angstroms radius around Nickel atom.
In total only one binding site of Nickel was determined in the Crystal Structure of Human LGR5-RSPO1-RNF43, PDB code: 4kng:

Nickel binding site 1 out of 1 in the Crystal Structure of Human LGR5-RSPO1-RNF43


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 1 of Crystal Structure of Human LGR5-RSPO1-RNF43 within 5.0Å range: probe atom residue distance (Å) B Occ B:Ni601 b:44.4 occ:1.00 CE1 A:HIS223 2.0 42.6 1.0 CE1 B:HIS223 2.0 35.8 1.0 ND1 A:HIS199 2.0 56.5 1.0 NE2 B:HIS223 2.1 31.4 1.0 CD2 B:HIS199 2.1 60.7 1.0 NE2 A:HIS223 2.1 34.3 1.0 CE1 A:HIS199 2.8 62.4 1.0 NE2 B:HIS199 2.9 68.1 1.0 CG A:HIS199 3.0 53.6 1.0 CG B:HIS199 3.0 55.6 1.0 ND1 A:HIS223 3.3 37.8 0.7 ND1 B:HIS223 3.3 30.7 0.3 CD2 B:HIS223 3.5 31.1 1.0 CD2 A:HIS223 3.5 34.9 1.0 CB A:HIS199 3.5 47.0 1.0 CB B:HIS199 3.6 46.2 1.0 NE2 A:HIS199 3.8 65.7 1.0 CD2 A:HIS199 3.9 59.1 1.0 CE1 B:HIS199 4.0 63.0 1.0 ND1 B:HIS199 4.0 63.0 1.0 CG A:HIS223 4.0 36.2 1.0 CG B:HIS223 4.0 29.4 1.0 O A:HIS199 4.5 32.0 1.0 O B:HIS199 4.6 35.7 1.0 C A:HIS199 4.7 33.1 1.0 CA A:HIS199 4.7 38.4 1.0 CA B:HIS199 4.9 39.1 1.0 C B:HIS199 4.9 36.1 1.0

P.H.Chen, X.Chen, Z.Lin, D.Fang, X.He. The Structural Basis of R-Spondin Recognition By LGR5 and RNF43. Genes Dev. V. 27 1345 2013.
ISSN: ISSN 0890-9369
PubMed: 23756651
DOI: 10.1101/GAD.219915.113