Nickel in PDB 4ziu: Crystal Structure of Native Alpha-2-Macroglobulin From Escherichia Coli Spanning the Residues From Domain MG7 to the C-Terminus.

The structure of Crystal Structure of Native Alpha-2-Macroglobulin From Escherichia Coli Spanning the Residues From Domain MG7 to the C-Terminus., PDB code: 4ziu was solved by I.Garcia-Ferrer, P.Arede, J.Gomez-Blanco, D.Luque, S.Duquerroy, J.R.Caston, T.Goulas, X.F.Gomis-Ruth, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.98 / 2.70
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	86.720, 136.190, 172.800, 90.00, 90.00, 90.00
R / Rfree (%)	19 / 24

The binding sites of Nickel atom in the Crystal Structure of Native Alpha-2-Macroglobulin From Escherichia Coli Spanning the Residues From Domain MG7 to the C-Terminus. (pdb code 4ziu). This binding sites where shown within 5.0 Angstroms radius around Nickel atom.
In total 2 binding sites of Nickel where determined in the Crystal Structure of Native Alpha-2-Macroglobulin From Escherichia Coli Spanning the Residues From Domain MG7 to the C-Terminus., PDB code: 4ziu:
Jump to Nickel binding site number: 1; 2;

Nickel binding site 1 out of 2 in the Crystal Structure of Native Alpha-2-Macroglobulin From Escherichia Coli Spanning the Residues From Domain MG7 to the C-Terminus.


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 1 of Crystal Structure of Native Alpha-2-Macroglobulin From Escherichia Coli Spanning the Residues From Domain MG7 to the C-Terminus. within 5.0Å range: probe atom residue distance (Å) B Occ A:Ni1701 b:63.2 occ:1.00 OE2 A:GLU1329 1.9 77.2 1.0 NE2 A:HIS1333 2.2 64.1 1.0 O2 A:GOL1704 2.3 77.8 1.0 CD A:GLU1329 2.9 92.0 1.0 C1 A:GOL1704 3.0 76.8 1.0 C2 A:GOL1704 3.1 79.0 1.0 CE1 A:HIS1333 3.2 63.4 1.0 OE1 A:GLU1329 3.3 88.1 1.0 CD2 A:HIS1333 3.3 63.5 1.0 O1 A:GOL1704 3.6 74.3 1.0 C3 A:GOL1704 3.7 80.2 1.0 CG A:GLU1329 4.3 62.5 1.0 ND1 A:HIS1333 4.4 62.8 1.0 CG A:HIS1333 4.4 60.5 1.0 O A:GLU1329 4.9 64.9 1.0 O3 A:GOL1704 5.0 81.3 1.0

Nickel binding site 2 out of 2 in the Crystal Structure of Native Alpha-2-Macroglobulin From Escherichia Coli Spanning the Residues From Domain MG7 to the C-Terminus.


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 2 of Crystal Structure of Native Alpha-2-Macroglobulin From Escherichia Coli Spanning the Residues From Domain MG7 to the C-Terminus. within 5.0Å range: probe atom residue distance (Å) B Occ A:Ni1702 b:73.1 occ:1.00 ND1 A:HIS1016 1.8 77.3 1.0 N A:GLY1015 2.1 69.2 1.0 N A:HIS1016 2.3 72.9 1.0 CE1 A:HIS1016 2.8 76.9 1.0 CG A:HIS1016 2.8 76.8 1.0 CA A:GLY1015 3.0 68.0 1.0 C A:GLY1015 3.0 73.5 1.0 CA A:HIS1016 3.2 72.7 1.0 CB A:HIS1016 3.3 74.5 1.0 N A:MET1017 3.9 75.0 1.0 NE2 A:HIS1016 3.9 77.8 1.0 CD2 A:HIS1016 4.0 78.0 1.0 C A:HIS1016 4.0 78.3 1.0 O A:GLY1015 4.2 71.8 1.0 O A:HOH1842 4.6 71.4 1.0 O A:HOH1868 4.8 80.1 1.0 CG A:MET1017 4.8 81.4 1.0

I.Garcia-Ferrer, P.Arede, J.Gomez-Blanco, D.Luque, S.Duquerroy, J.R.Caston, T.Goulas, F.X.Gomis-Ruth. Structural and Functional Insights Into Escherichia Coli Alpha 2-Macroglobulin Endopeptidase Snap-Trap Inhibition. Proc.Natl.Acad.Sci.Usa V. 112 8290 2015.
ISSN: ESSN 1091-6490
PubMed: 26100869
DOI: 10.1073/PNAS.1506538112