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Nickel in PDB 5wwx: Crystal Structure of the KH2 Domain of Human Rna-Binding E3 Ubiquitin- Protein Ligase Mex-3C Complex with Rna

Enzymatic activity of Crystal Structure of the KH2 Domain of Human Rna-Binding E3 Ubiquitin- Protein Ligase Mex-3C Complex with Rna

All present enzymatic activity of Crystal Structure of the KH2 Domain of Human Rna-Binding E3 Ubiquitin- Protein Ligase Mex-3C Complex with Rna:
2.3.2.27;

Protein crystallography data

The structure of Crystal Structure of the KH2 Domain of Human Rna-Binding E3 Ubiquitin- Protein Ligase Mex-3C Complex with Rna, PDB code: 5wwx was solved by L.Yang, C.Wang, F.Li, Q.Gong, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 33.37 / 2.00
Space group P 43 21 2
Cell size a, b, c (Å), α, β, γ (°) 74.611, 74.611, 32.535, 90.00, 90.00, 90.00
R / Rfree (%) 17 / 21.8

Nickel Binding Sites:

The binding sites of Nickel atom in the Crystal Structure of the KH2 Domain of Human Rna-Binding E3 Ubiquitin- Protein Ligase Mex-3C Complex with Rna (pdb code 5wwx). This binding sites where shown within 5.0 Angstroms radius around Nickel atom.
In total only one binding site of Nickel was determined in the Crystal Structure of the KH2 Domain of Human Rna-Binding E3 Ubiquitin- Protein Ligase Mex-3C Complex with Rna, PDB code: 5wwx:

Nickel binding site 1 out of 1 in 5wwx

Go back to Nickel Binding Sites List in 5wwx
Nickel binding site 1 out of 1 in the Crystal Structure of the KH2 Domain of Human Rna-Binding E3 Ubiquitin- Protein Ligase Mex-3C Complex with Rna


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 1 of Crystal Structure of the KH2 Domain of Human Rna-Binding E3 Ubiquitin- Protein Ligase Mex-3C Complex with Rna within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ni401

b:25.7
occ:0.50
NE2 A:HIS314 2.0 13.0 1.0
NE2 A:HIS316 2.1 19.5 1.0
CE1 A:HIS314 3.0 18.6 1.0
CD2 A:HIS314 3.0 17.6 1.0
CD2 A:HIS316 3.0 16.4 1.0
CE1 A:HIS316 3.1 16.6 1.0
ND1 A:HIS314 4.1 20.2 1.0
CG A:HIS314 4.1 19.0 1.0
CG A:HIS316 4.2 18.5 1.0
ND1 A:HIS316 4.2 16.8 1.0
O2 C:U5 4.3 18.3 1.0
O A:HOH522 4.7 36.2 1.0
C2 C:U5 5.0 17.9 1.0
N3 C:U5 5.0 18.8 1.0

Reference:

L.Yang, C.Wang, F.Li, J.Zhang, A.Nayab, J.Wu, Y.Shi, Q.Gong. The Human Rna-Binding Protein and E3 Ligase Mex-3C Binds the Mex-3-Recognition Element (Mre) Motif with High Affinity J. Biol. Chem. V. 292 16221 2017.
ISSN: ESSN 1083-351X
PubMed: 28808060
DOI: 10.1074/JBC.M117.797746
Page generated: Wed Dec 16 01:49:34 2020

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