Nickel in PDB 6ncy: Crystal Structure of Hybrid Beta-Glucuronidase/Beta-Galacturonidase From Fusicatenibacter Saccharivorans

All present enzymatic activity of Crystal Structure of Hybrid Beta-Glucuronidase/Beta-Galacturonidase From Fusicatenibacter Saccharivorans:
3.2.1.31;

The structure of Crystal Structure of Hybrid Beta-Glucuronidase/Beta-Galacturonidase From Fusicatenibacter Saccharivorans, PDB code: 6ncy was solved by W.G.Walton, S.J.Pellock, M.R.Redinbo, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.71 / 2.05
Space group	P 21 3
Cell size a, b, c (Å), α, β, γ (°)	192.562, 192.562, 192.562, 90.00, 90.00, 90.00
R / Rfree (%)	15.4 / 18

The binding sites of Nickel atom in the Crystal Structure of Hybrid Beta-Glucuronidase/Beta-Galacturonidase From Fusicatenibacter Saccharivorans (pdb code 6ncy). This binding sites where shown within 5.0 Angstroms radius around Nickel atom.
In total 2 binding sites of Nickel where determined in the Crystal Structure of Hybrid Beta-Glucuronidase/Beta-Galacturonidase From Fusicatenibacter Saccharivorans, PDB code: 6ncy:
Jump to Nickel binding site number: 1; 2;

Nickel binding site 1 out of 2 in the Crystal Structure of Hybrid Beta-Glucuronidase/Beta-Galacturonidase From Fusicatenibacter Saccharivorans


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 1 of Crystal Structure of Hybrid Beta-Glucuronidase/Beta-Galacturonidase From Fusicatenibacter Saccharivorans within 5.0Å range: probe atom residue distance (Å) B Occ A:Ni701 b:72.7 occ:1.00 O A:HOH995 1.9 42.6 1.0 O A:HOH1296 2.6 56.8 1.0 NE2 A:HIS501 3.6 27.1 1.0 ND1 A:HIS499 4.0 34.1 1.0 CD2 A:HIS501 4.3 25.9 1.0 CE1 A:HIS501 4.5 29.5 1.0 O A:HOH999 4.6 35.5 1.0 CB A:HIS499 4.7 29.8 1.0 CG A:HIS499 4.8 32.6 1.0 CA A:HIS499 4.8 28.0 1.0 OH A:TYR566 4.9 29.3 1.0 CE1 A:HIS499 4.9 33.8 1.0

Nickel binding site 2 out of 2 in the Crystal Structure of Hybrid Beta-Glucuronidase/Beta-Galacturonidase From Fusicatenibacter Saccharivorans


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 2 of Crystal Structure of Hybrid Beta-Glucuronidase/Beta-Galacturonidase From Fusicatenibacter Saccharivorans within 5.0Å range: probe atom residue distance (Å) B Occ B:Ni701 b:71.7 occ:1.00 O B:HOH842 1.9 38.0 1.0 O B:HOH1307 3.0 56.3 1.0 O B:HOH1242 3.4 51.7 1.0 O B:HOH1285 3.5 56.1 1.0 NE2 B:HIS501 3.6 27.0 1.0 ND1 B:HIS499 3.8 35.5 1.0 CD2 B:HIS501 4.2 26.5 1.0 CE1 B:HIS501 4.4 28.9 1.0 CB B:HIS499 4.5 31.1 1.0 CG B:HIS499 4.6 33.2 1.0 CE1 B:HIS499 4.7 32.6 1.0 CA B:HIS499 4.7 27.8 1.0 OH B:TYR566 5.0 30.1 1.0

S.J.Pellock, W.G.Walton, M.R.Redinbo. Selecting A Single Stereocenter: the Molecular Nuances That Differentiate Beta-Hexuronidases in the Human Gut Microbiome. Biochemistry V. 58 1311 2019.
ISSN: ISSN 1520-4995
PubMed: 30729778
DOI: 10.1021/ACS.BIOCHEM.8B01285