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Nickel in PDB 6y6s: Mouse Galactocerebrosidase Complexed with Galacto-Noeurostegine Gns at pH 6.8
Enzymatic activity of Mouse Galactocerebrosidase Complexed with Galacto-Noeurostegine Gns at pH 6.8
All present enzymatic activity of Mouse Galactocerebrosidase Complexed with Galacto-Noeurostegine Gns at pH 6.8:
3.2.1.46;
3.2.1.46;
Protein crystallography data
The structure of Mouse Galactocerebrosidase Complexed with Galacto-Noeurostegine Gns at pH 6.8, PDB code: 6y6s
was solved by
J.E.Deane,
J.Mcloughlin,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 56.07 / 2.10 |
| Space group | H 3 2 |
| Cell size a, b, c (Å), α, β, γ (°) | 248.721, 248.721, 77.326, 90, 90, 120 |
| R / Rfree (%) | 16.3 / 20.1 |
Other elements in 6y6s:
The structure of Mouse Galactocerebrosidase Complexed with Galacto-Noeurostegine Gns at pH 6.8 also contains other interesting chemical elements:
| Calcium | (Ca) | 1 atom |
Nickel Binding Sites:
The binding sites of Nickel atom in the Mouse Galactocerebrosidase Complexed with Galacto-Noeurostegine Gns at pH 6.8
(pdb code 6y6s). This binding sites where shown within
5.0 Angstroms radius around Nickel atom.
In total only one binding site of Nickel was determined in the Mouse Galactocerebrosidase Complexed with Galacto-Noeurostegine Gns at pH 6.8, PDB code: 6y6s:
In total only one binding site of Nickel was determined in the Mouse Galactocerebrosidase Complexed with Galacto-Noeurostegine Gns at pH 6.8, PDB code: 6y6s:
Nickel binding site 1 out of 1 in 6y6s
Go back to
Nickel Binding Sites List in 6y6s
Nickel binding site 1 out
of 1 in the Mouse Galactocerebrosidase Complexed with Galacto-Noeurostegine Gns at pH 6.8
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Nickel with other atoms in the Ni binding
site number 1 of Mouse Galactocerebrosidase Complexed with Galacto-Noeurostegine Gns at pH 6.8 within 5.0Å range:
|
Reference:
A.Viuff,
S.Salamone,
J.Mcloughlin,
J.E.Deane,
H.H.Jensen.
The Bicyclic Form of Galacto-Noeurostegine Is A Potent Inhibitor of Beta-Galactocerebrosidase Acs Med.Chem.Lett. 2020.
ISSN: ISSN 1948-5875
DOI: 10.1021/ACSMEDCHEMLETT.0C00377
Page generated: Thu Oct 10 08:59:45 2024
ISSN: ISSN 1948-5875
DOI: 10.1021/ACSMEDCHEMLETT.0C00377
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