Nickel in PDB 3n6l: The Crystal Strucutre of Rna-Dependent Rna Polymerase of EV71 Virus

The structure of The Crystal Strucutre of Rna-Dependent Rna Polymerase of EV71 Virus, PDB code: 3n6l was solved by Y.Wu, Z.H.Rao, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.60
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	103.450, 103.450, 132.243, 90.00, 90.00, 120.00
R / Rfree (%)	21.9 / 26.9

The binding sites of Nickel atom in the The Crystal Strucutre of Rna-Dependent Rna Polymerase of EV71 Virus (pdb code 3n6l). This binding sites where shown within 5.0 Angstroms radius around Nickel atom.
In total only one binding site of Nickel was determined in the The Crystal Strucutre of Rna-Dependent Rna Polymerase of EV71 Virus, PDB code: 3n6l:

Nickel binding site 1 out of 1 in the The Crystal Strucutre of Rna-Dependent Rna Polymerase of EV71 Virus


Mono view


Stereo pair view

A full contact list of Nickel with other atoms in the Ni binding site number 1 of The Crystal Strucutre of Rna-Dependent Rna Polymerase of EV71 Virus within 5.0Å range: probe atom residue distance (Å) B Occ A:Ni463 b:38.1 occ:1.00 NE2 A:HIS273 2.0 32.5 1.0 SG A:CYS282 2.2 41.1 1.0 NE2 A:HIS271 2.2 42.7 1.0 O A:HOH466 2.3 15.0 1.0 CD2 A:HIS273 2.9 33.9 1.0 CE1 A:HIS271 3.1 41.8 1.0 CE1 A:HIS273 3.1 35.4 1.0 CB A:CYS282 3.3 40.7 1.0 CD2 A:HIS271 3.3 39.9 1.0 NE1 A:TRP5 4.0 45.6 1.0 CG A:HIS273 4.1 37.4 1.0 ND1 A:HIS273 4.2 37.1 1.0 ND1 A:HIS271 4.2 40.6 1.0 CZ2 A:TRP5 4.2 46.2 1.0 CG A:HIS271 4.4 38.5 1.0 CE2 A:TRP5 4.4 45.4 1.0 CA A:CYS282 4.4 40.6 1.0 O A:THR272 5.0 37.6 1.0

Y.Wu, Z.Lou, Y.Miao, Y.Yu, H.Dong, W.Peng, M.Bartlam, X.Li, Z.Rao. Structures of EV71 Rna-Dependent Rna Polymerase in Complex with Substrate and Analogue Provide A Drug Target Against the Hand-Foot-and-Mouth Disease Pandemic in China. Protein Cell V. 1 491 2010.
ISSN: ISSN 1674-800X
PubMed: 21203964
DOI: 10.1007/S13238-010-0061-7